Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.44 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.43 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.43 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.43 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | CHAT | P28329 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356356 | 1.00 | KMT2A (0.52) | KMT2AMEN1THRBGLO1SENP3 | |
| SCHEMBL28467677 | 0.93 | THRB (0.61) | KMT2AMEN1THRBGLO1SENP3 | |
| SCHEMBL2862763 | 0.92 | SNCA (0.45) | KMT2AMEN1THRBGLO1SENP3 | |
| SCHEMBL29425663 | 0.92 | SNCA (0.45) | KMT2AMEN1THRBGLO1SENP3 | |
| SCHEMBL591337 | 0.87 | THRB (0.53) | KMT2AMEN1THRBCHATSNCA | |
| SCHEMBL2862964 | 0.87 | THRB (0.53) | KMT2AMEN1THRBCHATSNCA | |
| SCHEMBL29353590 | 0.87 | THRB (0.53) | KMT2AMEN1THRBCHATSNCA | |
| SCHEMBL29401264 | 0.84 | KMT2A (0.71) | KMT2AMEN1THRBGLO1SENP3 | |
| SCHEMBL15276051 | 0.84 | KMT2A (0.71) | KMT2AMEN1THRBGLO1SENP3 | |
| SCHEMBL28414211 | 0.84 | KMT2A (0.69) | KMT2AMEN1THRBGLO1SENP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188373-A1 | METHOD FOR DETECTING WATER-SOLUBLE ANIONIC SYNTHETIC PIGMENT IN FOOD | 广州市食品检验所（广州市酒类检测中心） | 2022-09-15 | — | — | WO | disclosed |
| US-20210115489-A1 | NOVEL MEDIATOR | KIKKOMAN CORPORATION (JP) | 2021-04-22 | — | — | US | disclosed |
| EP-3780207-A1 | NOVEL MEDIATOR | Kikkoman Corporation (JP) | 2021-02-17 | — | — | EP | disclosed |
| CN-111296492-A | Diatomite-tea geometrid nuclear polyhedrosis virus composition and application thereof | 广西益才农业发展有限公司 | 2020-06-19 | — | — | CN | disclosed |
| US-10589003-B2 | Methods for coating surfaces with antimicrobial agents | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-03-17 | — | — | US | disclosed |
| EP-3533859-A1 | CLEANING COMPOSITIONS | The Procter & Gamble Company (US) | 2019-09-04 | — | — | EP | disclosed |
| EP-3533858-A1 | CLEANING COMPOSITION COMPRISING A GLYCOGEN-DEBRANCHING ENZYME AND METHODS OF CLEANING | The Procter & Gamble Company (US) | 2019-09-04 | — | — | EP | disclosed |
| US-20190264139-A1 | CLEANING COMPOSITIONS | THE PROCTER AND GAMBLE COMPANY | 2019-08-29 | — | — | US | disclosed |
| US-20190264140-A1 | METHODS OF CLEANING | THE PROCTER AND GAMBLE COMPANY | 2019-08-29 | — | — | US | disclosed |
| EP-3246462-B1 | COLOUR TRANSFER-INHIBITING MATERIAL | ACONDICIONAMIENTO TARRASENSE (ES) | 2018-11-28 | — | — | EP | disclosed |
| WO-2017194331-A1 | USE OF POLYIMIDAZOLIUM SALTS AS DYE TRANSFER INHIBITORS | BASF SE (DE) | 2017-11-16 | — | — | WO | disclosed |
| EP-2961820-B1 | COLOR-PROTECTING DETERGENT | HENKEL AG & CO KGAA (DE) | 2017-09-13 | — | — | EP | disclosed |
| US-20170035683-A1 | NON-AQUEOUS HAIR BLEACHING AND COLORING COMPOSITIONS, METHODS OF MANUFACTURING SAME AND METHODS OF USE | BRIGHT INTERNATIONAL CORP. (US) | 2017-02-09 | — | — | US | disclosed |
| US-9546344-B2 | Color-protecting detergent | HENKEL AG & CO. KGAA (DE) | 2017-01-17 | — | — | US | disclosed |
| US-20150368590-A1 | COLOR-PROTECTING DETERGENT | HENKEL AG & CO. KGAA (DE) | 2015-12-24 | — | — | US | disclosed |
| US-7713472-B2 | Antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-05-11 | — | — | US | disclosed |
| US-7651661-B2 | Medical devices with broad spectrum antimicrobial activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-01-26 | — | — | US | disclosed |
| US-20080183152-A1 | MEDICAL DEVICES WITH BROAD SPECTRUM ANTIMICROBIAL ACTIVITY | RAAD ISSAM | 2008-07-31 | — | — | US | disclosed |
| US-20070154621-A1 | METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2007-07-05 | — | — | US | disclosed |
| US-20050197634-A1 | Methods for coating and impregnating medical devices with antiseptic compositions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115489-A1 | NOVEL MEDIATOR | MPO, EPX, LPO | THRB 4364/4885KMT2A 3104/4885MEN1 2351/4885 |
| US-10589003-B2 | Methods for coating surfaces with antimicrobial agents | CUTA, CD63, CDC37 | THRB 4713/4885KMT2A 3316/4885MEN1 4111/4885 |
| US-20170035683-A1 | NON-AQUEOUS HAIR BLEACHING AND COLORING COMPOSITIONS, METHODS OF MANUFACTURING SAME AND METHODS OF USE | SMOX, TET2, TST | THRB 3469/4885KMT2A 1342/4885MEN1 2265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.