Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 15/20 | 0.47 |
| ▸ | CNR1 | P21554 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868709 | 0.98 | THRB (0.53) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL2859161 | 0.95 | THRB (0.56) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL9108467 | 0.94 | THRB (0.51) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL124487 | 0.88 | THRB (0.50) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL20740546 | 0.86 | THRB (0.48) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL29413087 | 0.85 | THRB (0.50) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL1925726 | 0.85 | SNCA (0.55) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL126069 | 0.84 | THRB (0.47) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL9106113 | 0.82 | THRB (0.53) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL341270 | 0.81 | THRB (0.45) | THRBMEN1KMT2ATDP1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984303-B2 | Electrochemical production of dyes using graphite felt electrodes | NOVEON IP HOLDINGS CORP. (US) | 2006-01-10 | — | — | US | claimed |
| US-20040163968-A1 | Electrochemical production of dyes using graphite felt electrodes | EMERALD HILTON DAVIS, LLC | 2004-08-26 | — | — | US | claimed |
| WO-2004013178-A1 | FUSION PROTEINS BETWEEN A FLUORESCENT PROTEIN AND AN IONOTROPIC RECEPTOR AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2004-02-12 | — | — | WO | claimed |
| EP-0986759-A2 | USE OF A FLUORESCENT PROTEIN FOR DETECTING INTERACTION BETWEEN A TARGET PROTEIN AND ITS LIGAND | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2000-03-22 | — | — | EP | claimed |
| WO-1998055873-A2 | USE OF A FLUORESCENT PROTEIN FOR DETECTING INTERACTION BETWEEN A TARGET PROTEIN AND ITS LIGAND | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-12-10 | — | — | WO | claimed |
| US-20250018066-A1 | Ophthalmic dye composition | VITREQ B.V. (NL) | 2025-01-16 | — | — | US | disclosed |
| US-20210213144-A1 | OPHTHALMIC DYE COMPOSITION | VITREQ B.V. (NL) | 2021-07-15 | — | — | US | disclosed |
| US-10589003-B2 | Methods for coating surfaces with antimicrobial agents | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-03-17 | — | — | US | disclosed |
| US-20180303977-A1 | METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-10-25 | — | — | US | disclosed |
| CN-108587237-A | A kind of polymolecularity acid dyes and preparation method thereof | 浩沙实业（福建）有限公司 | 2018-09-28 | — | — | CN | disclosed |
| WO-2018007457-A1 | OPHTHALMIC DYE | VITREQ B.V. (NL) | 2018-01-11 | — | — | WO | disclosed |
| WO-2017182620-A2 | OPHTHALMIC DYE COMPOSITION | VITREQ B.V. (NL) | 2017-10-26 | — | — | WO | disclosed |
| EP-1514112-A2 | METHOD FOR ISOLATING AN ALLOSTERIC EFFECTOR OF A RECEPTOR | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-03-16 | — | — | EP | disclosed |
| US-20040163968-A1 | Electrochemical production of dyes using graphite felt electrodes | EMERALD HILTON DAVIS, LLC | 2004-08-26 | — | — | US | disclosed |
| WO-2004013178-A1 | FUSION PROTEINS BETWEEN A FLUORESCENT PROTEIN AND AN IONOTROPIC RECEPTOR AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2004-02-12 | — | — | WO | disclosed |
| EP-1372581-A1 | COMPOSITION FOR SIMULTANEOUSLY LIGHTENING AND COLORING HAIR UTILIZING BLEACH-STABLE ACID AND BASIC DYES | L'Avant Garde Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2003107004-A2 | METHOD FOR ISOLATING AN ALLOSTERIC EFFECTOR OF A RECEPTOR | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2003-12-24 | — | — | WO | disclosed |
| WO-2002074270-A1 | COMPOSITION FOR SIMULTANEOUSLY LIGHTENING AND COLORING HAIR UTILIZING BLEACH-STABLE ACID AND BASIC DYES | L'AVANT GARDE INC. (US) | 2002-09-26 | — | — | WO | disclosed |
| EP-0986759-A2 | USE OF A FLUORESCENT PROTEIN FOR DETECTING INTERACTION BETWEEN A TARGET PROTEIN AND ITS LIGAND | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998055873-A2 | USE OF A FLUORESCENT PROTEIN FOR DETECTING INTERACTION BETWEEN A TARGET PROTEIN AND ITS LIGAND | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10589003-B2 | Methods for coating surfaces with antimicrobial agents | CUTA, CD63, CDC37 | THRB 4713/4885MEN1 4111/4885KMT2A 3316/4885 |
| US-20180303977-A1 | METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS | CUTA, CD63, CDC37 | THRB 4713/4885MEN1 4111/4885KMT2A 3316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.