Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625617 | 0.96 | CHRM2 (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL24752922 | 0.74 | CHRM2 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL3417328 | 0.73 | — | — | |
| SCHEMBL1621071 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL176040 | 0.71 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9296811 | 0.70 | — | — | |
| SCHEMBL4009724 | 0.68 | CHRM2 (0.31) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL15095887 | 0.68 | CHRM2 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12700286 | 0.68 | CHRM2 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8515490 | 0.68 | CHRM2 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134515-A1 | NOVEL COMPOUND AS RON INHIBITOR | 주식회사 엘지화학 | 2024-06-27 | — | — | WO | claimed |
| US-10202345-B2 | Substituted azaspiro(4.5)decane derivatives | GRUENENTHAL GMBH (DE) | 2019-02-12 | — | — | US | disclosed |
| US-10072180-B2 | Composition for preparing article containing poly(imide-amide), method of preparing the same, and article containing poly(imide-amide) | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2018-09-11 | — | — | US | disclosed |
| US-10059805-B2 | Composition for preparing polyimide-inorganic particle composite, article prepared therefrom, and optical device comprising same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2018-08-28 | — | — | US | disclosed |
| US-20160222249-A1 | COMPOSITION FOR PREPARING ARTICLE CONTAINING POLY(IMIDE-AMIDE), METHOD OF PREPARING THE SAME, AND ARTICLE CONTAINING POLY(IMIDE-AMIDE) | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-08-04 | — | — | US | disclosed |
| US-20160096927-A1 | COMPOSITION FOR PREPARING POLYIMIDE-INORGANIC PARTICLE COMPOSITE, ARTICLE PREPARED THEREFROM, AND OPTICAL DEVICE COMPRISING SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-04-07 | — | — | US | disclosed |
| US-20160016903-A1 | Substituted Azaspiro(4.5)Decane Derivatives | GRUENENTHAL GMBH (DE) | 2016-01-21 | — | — | US | disclosed |
| US-9051315-B2 | Imidazopyridines as a novel scaffold for multi-targeted kinase inhibition | ABBVIE INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20150152223-A1 | POLYMER FOR OPTICAL FILM, AND OPTICAL FILM INCLUDING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-06-04 | — | — | US | disclosed |
| EP-2427459-A1 | ISOXAZOLE-THIAZOLE DERIVATIVES AS GABA A RECEPTOR INVERSE AGONISTS FOR USE IN THE TREATMENT OF COGNITIVE DISORDERS | F. Hoffmann-La Roche AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| EP-2427458-A1 | ISOXAZOLE-PYRIDAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| US-20110124632-A1 | IMIDAZOPYRIDINES AS A NOVEL SCAFFOLD FOR MULTI-TARGETED KINASE INHIBITION | ABBOTT LABORATORIES (US) | 2011-05-26 | — | — | US | disclosed |
| US-20110112076-A1 | SELECTIVE HYDROXAMIC ACID BASED MMP-12 AND MMP-13 INHIBITORS | NOVARTIS AG (CH) | 2011-05-12 | — | — | US | disclosed |
| EP-2318361-A1 | SELECTIVE HYDROXAMIC ACID BASED MMP-12 AND MMP-13 INHIBITORS | Novartis AG (CH) | 2011-05-11 | — | — | EP | disclosed |
| US-20110039845-A1 | 2-AMINOQUINAZOLINE DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2011-02-17 | — | — | US | disclosed |
| US-20050222093-A1 | Methods for restoring cognitive function following systemic stress | PEARLMAN RODNEY | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222093-A1 | Methods for restoring cognitive function following systemic stress | CRH, BDNF, CHAT | CHRM2 95/4885CHRM4 42/4885CHRM5 48/4885 |
| US-20110039845-A1 | 2-AMINOQUINAZOLINE DERIVATIVE | H1-2, H1-3, H1-0 | CHRM2 585/4885CHRM4 2083/4885CHRM5 1277/4885 |
| US-10202345-B2 | Substituted azaspiro(4.5)decane derivatives | OPRL1, OPRD1, OPRM1 | CHRM2 627/4885CHRM4 544/4885CHRM5 244/4885 |
| US-20110112076-A1 | SELECTIVE HYDROXAMIC ACID BASED MMP-12 AND MMP-13 INHIBITORS | MMP13, MMP11, MMP14 | CHRM2 4793/4885CHRM4 4862/4885CHRM5 4835/4885 |
| US-20160016903-A1 | Substituted Azaspiro(4.5)Decane Derivatives | OPRL1, OPRD1, OPRM1 | CHRM2 627/4885CHRM4 544/4885CHRM5 244/4885 |
| US-20110124632-A1 | IMIDAZOPYRIDINES AS A NOVEL SCAFFOLD FOR MULTI-TARGETED KINASE INHIBITION | PACSIN2, MAP4K2, MAP3K6 | CHRM2 4641/4885CHRM4 4383/4885CHRM5 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.