Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 known ✓ | P35354 | 3/20 | 0.46 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1339762 | 0.82 | BCAT2 (0.51) | PTGS2BCAT2ALDH1A1MAPTTSHR | |
| SCHEMBL2231308 | 0.81 | BCAT2 (0.69) | PTGS2BCAT2ALDH1A1MAPTTSHR | |
| SCHEMBL8792437 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTTSHRMAPK1HSD17B10 | |
| SCHEMBL8089263 | 0.69 | PTGS2 (0.49) | PTGS2ALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL28930331 | 0.68 | PTGS2 (0.60) | PTGS2ALDH1A1PTGS1 | |
| SCHEMBL28228496 | 0.67 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL3988930 | 0.67 | PTGS2 (0.44) | PTGS2ALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL6918591 | 0.67 | AKR1C3 (0.46) | PTGS2BCAT2ALDH1A1MAPTTSHR | |
| SCHEMBL7462691 | 0.67 | PTGS2 (0.47) | PTGS2ALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL11043222 | 0.67 | PTGS2 (0.51) | PTGS2ALDH1A1MAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754509-A | Method for preparing conjugated diene with single stereo configuration from allyl alcohol compound | 中山大学 | 2021-12-07 | — | — | CN | claimed |