Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.64 |
| ▸ | CA1 | P00915 | 5/20 | 0.64 |
| ▸ | CA9 | Q16790 | 5/20 | 0.64 |
| ▸ | CA12 | O43570 | 4/20 | 0.64 |
| ▸ | CA4 | P22748 | 4/20 | 0.64 |
| ▸ | CA6 | P23280 | 3/20 | 0.64 |
| ▸ | CA5A | P35218 | 3/20 | 0.64 |
| ▸ | CA7 | P43166 | 3/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.45 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101353 | 0.95 | CA2 (0.64) | CA2CA1CA9CA12CA4 | |
| Potassium Ion SCHEMBL11742565 | 0.82 | CA2 (0.67) | CA2CA1CA9CA12CA4 | |
| Potassium Ion SCHEMBL38471 | 0.81 | HTR6 (0.50) | CA2CA1CA9CA12CA4 | |
| SCHEMBL6680428 | 0.80 | CA1 (0.70) | CA2CA1CA9CA12CA4 | |
| Potassium Ion SCHEMBL1538011 | 0.79 | LMNA (0.48) | CA2CA1CA9CA12CA4 | |
| Hydrochloric Acid SCHEMBL3956091 | 0.78 | CA1 (0.71) | CA2CA1CA9CA12CA4 | |
| SCHEMBL27257080 | 0.78 | CA2 (0.67) | CA2CA1CA9CA12CA4 | |
| Mafenide SCHEMBL9295695 | 0.78 | CA2 (1.00) | CA2CA1CA9CA12CA4 | |
| Mafenide SCHEMBL41628 | 0.78 | CA2 (1.00) | CA2CA1CA9CA12CA4 | |
| SCHEMBL4101241 | 0.77 | CA2 (0.67) | CA2CA1CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510385-A | Chain transfer agent for polycarboxylate superplasticizer, application and preparation method thereof | 科之杰新材料集团(贵州)有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117510385-A | Chain transfer agent for polycarboxylate superplasticizer, application and preparation method thereof | 科之杰新材料集团(贵州)有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-114014788-B | Chain transfer agent for polycarboxylate superplasticizer, application and preparation method thereof | 科之杰新材料集团(贵州)有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-114014788-A | Chain transfer agent for polycarboxylate superplasticizer, application and preparation method thereof | 科之杰新材料集团(贵州)有限公司 | 2022-02-08 | — | — | CN | disclosed |