Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 6/20 | 0.64 |
| ▸ | CA1 known ✓ | P00915 | 5/20 | 0.64 |
| ▸ | CA12 known ✓ | O43570 | 4/20 | 0.64 |
| ▸ | CA4 known ✓ | P22748 | 4/20 | 0.64 |
| ▸ | CA9 | Q16790 | 5/20 | 0.64 |
| ▸ | CA6 | P23280 | 3/20 | 0.64 |
| ▸ | CA5A | P35218 | 3/20 | 0.64 |
| ▸ | CA7 | P43166 | 3/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.45 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL28680277 | 0.95 | CA2 (0.64) | CA2CA1CA9CA12CA4 | |
| SCHEMBL4101241 | 0.82 | CA2 (0.67) | CA2CA1CA9CA12CA4 | |
| SCHEMBL6680428 | 0.80 | CA1 (0.70) | CA2CA1CA9CA12CA4 | |
| SCHEMBL11058236 | 0.79 | CA1 (0.45) | CA2CA1CA9CA12CA4 | |
| SCHEMBL19953365 | 0.79 | LMNA (0.55) | CA2CA1CA9CA12CA4 | |
| SCHEMBL8954100 | 0.79 | CA2 (0.52) | CA2CA1CA9CA12CA4 | |
| Mafenide SCHEMBL41628 | 0.78 | CA2 (1.00) | CA2CA1CA9CA12CA4 | |
| Hydrochloric Acid SCHEMBL3956091 | 0.78 | CA1 (0.71) | CA2CA1CA9CA12CA4 | |
| Mafenide SCHEMBL9295695 | 0.78 | CA2 (1.00) | CA2CA1CA9CA12CA4 | |
| SCHEMBL27257080 | 0.78 | CA2 (0.67) | CA2CA1CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510385-A | Chain transfer agent for polycarboxylate superplasticizer, application and preparation method thereof | 科之杰新材料集团(贵州)有限公司 | 2024-02-06 | — | — | CN | claimed |
| WO-1994002497-A1 | SULFO-DERIVATIVES OF ADENOSINE | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-02-03 | — | — | WO | claimed |
| CN-117510385-A | Chain transfer agent for polycarboxylate superplasticizer, application and preparation method thereof | 科之杰新材料集团(贵州)有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-114014788-B | Chain transfer agent for polycarboxylate superplasticizer, application and preparation method thereof | 科之杰新材料集团(贵州)有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-114014788-A | Chain transfer agent for polycarboxylate superplasticizer, application and preparation method thereof | 科之杰新材料集团(贵州)有限公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-112881311-A | Creatine kinase detection reagent, kit and detection method | 深圳迈瑞生物医疗电子股份有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-106928129-A | A kind of cathodic electrochromic compound in electrochromic device | 宁波祢若电子科技有限公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-106916099-A | A kind of cathodic electrochromic compound in electrochromic device and preparation method thereof | 宁波祢若电子科技有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-106916582-A | A kind of cathodic electrochromic compound and associated media and device | 宁波祢若电子科技有限公司 | 2017-07-04 | — | — | CN | disclosed |
| US-20090076140-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING SULPHONIC ACID DERIVATIVES | ITALFARMACO, S. A. (ES) | 2009-03-19 | — | — | US | disclosed |
| US-20060160849-A1 | Pharmaceutical compositions containing sulphonic acid derivatives | ITALFARMACO, S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
| EP-1602644-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING SULPHONIC ACID DERIVATIVES | Italfarmaco, S.A. (ES) | 2005-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076140-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING SULPHONIC ACID DERIVATIVES | SUCNR1, NR1H4, CYP2B6 | CA2 348/4885CA1 902/4885CA12 250/4885 |
| US-20060160849-A1 | Pharmaceutical compositions containing sulphonic acid derivatives | SUCNR1, NR1H4, CYP2B6 | CA2 329/4885CA1 880/4885CA12 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.