Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | GRK2 | P25098 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | PLEC | Q15149 | 1/20 | 0.66 |
| ▸ | APP | P05067 | 1/20 | 0.66 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.48 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859446 | 1.00 | POLB (0.66) | POLBMEN1GRK2KMT2APLEC | |
| SCHEMBL29538678 | 1.00 | POLB (0.66) | POLBMEN1GRK2KMT2APLEC | |
| SCHEMBL29396086 | 0.94 | MEN1 (0.70) | POLBMEN1GRK2KMT2APLEC | |
| SCHEMBL7558820 | 0.94 | MEN1 (0.70) | POLBMEN1GRK2KMT2APLEC | |
| SCHEMBL11791648 | 0.91 | MEN1 (0.66) | POLBMEN1GRK2KMT2APLEC | |
| SCHEMBL11791659 | 0.91 | MEN1 (0.66) | POLBMEN1GRK2KMT2APLEC | |
| SCHEMBL29355238 | 0.89 | MEN1 (0.65) | POLBMEN1GRK2KMT2APLEC | |
| SCHEMBL4806483 | 0.88 | USP2 (0.66) | POLBMEN1GRK2KMT2APLEC | |
| SCHEMBL29354476 | 0.88 | USP2 (0.66) | POLBMEN1GRK2KMT2APLEC | |
| SCHEMBL186094 | 0.88 | USP2 (0.66) | POLBMEN1GRK2KMT2APLEC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 647 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109439016-B | Red sun-proof acid dye and preparation method thereof | 绍兴金美珂化工有限公司 | 2020-04-07 | — | — | CN | claimed |
| US-10384203-B2 | Kits and devices for detecting analytes | FIRST LIGHT BIOSCIENCES, INC. (US) | 2019-08-20 | — | — | US | claimed |
| US-20170315031-A1 | TISSUE AND CELL STAIN FORMULA WITH A NOVEL MOLECULE OBTAINED FROM PAPAVER RHOEAS | BUDAK MEHMET (TR) | 2017-11-02 | — | — | US | claimed |
| EP-3209292-A1 | TISSUE AND CELL STAIN FORMULA WITH A NOVEL MOLECULE OBTAINED FROM PAPAVER RHOEAS | Budak, Mehmet (TR) | 2017-08-30 | — | — | EP | claimed |
| EP-1463781-B1 | USE OF A DYESTUFF FOR INK JET PRINTING RECORDING MATERIALS | CLARIANT FINANCE BVI LTD (VG) | 2008-04-30 | — | — | EP | claimed |
| US-7153332-B2 | Use of a dyestuff for ink jet printing recording materials | CLARIANT FINANCE (BVI) LIMITED (VG) | 2006-12-26 | — | — | US | claimed |
| US-7067324-B2 | Photon reducing agents for fluorescence assays | INVITROGEN CORPORATION (US) | 2006-06-27 | — | — | US | claimed |
| US-6998185-B2 | Dye-based fuel indicator system for fuel cells | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2006-02-14 | — | — | US | claimed |
| US-20050120495-A1 | Use of a dyestuff for ink jet printing recording materials | CLARIANT FINANCE (BVI) LIMITED (VG) | 2005-06-09 | — | — | US | claimed |
| US-6828152-B2 | Reagentless method for determining the concentration of one or more analytes in blood, synovial fluid, semen, feces and cerebrospinal fluid via spectrophotometry; hemolysis | SPECTROMEDICAL INC. (CA) | 2004-12-07 | — | — | US | claimed |
| EP-0618949-A1 | IONIC DYE-BASED ELECTRORHEOLOGICAL MATERIALS | LORD CORPORATION (US) | 1994-10-12 | — | — | EP | claimed |
| EP-0618949-A4 | IONIC DYE-BASED ELECTRORHEOLOGICAL MATERIALS. | LORD CORP (US) | 1994-07-07 | — | — | EP | claimed |
| US-5306438-A | Dielectric hydrophobic liquid carrier fluid with anionic dye particles; quick response | LORD CORPORATION (US) | 1994-04-26 | — | — | US | claimed |
| WO-1993019143-A1 | COLORANT-CONTAINING ELECTRORHEOLOGICAL MATERIALS | LORD CORPORATION (US) | 1993-09-30 | — | — | WO | claimed |
| WO-1993012192-A1 | IONIC DYE-BASED ELECTRORHEOLOGICAL MATERIALS | LORD CORPORATION (US) | 1993-06-24 | — | — | WO | claimed |
| US-5094545-A | Solid solution with nucleating agent and indicator dye | PYMA CORPORATION (US) | 1992-03-10 | — | — | US | claimed |
| US-4362645-A | Temperature indicating compositions of matter | AKZONA, INC. (US) | 1982-12-07 | — | — | US | claimed |
| US-4345470-A | All plastic disposable thermometer | AKZONA INCORPORATED (US) | 1982-08-24 | — | — | US | claimed |
| US-4299727-A | Disposable reversible thermometer | AKZONA INCORPORATED (US) | 1981-11-10 | — | — | US | claimed |
| US-4232552-A | THERMOCHROMISM, DISPOSABLE THERMOMETERS | AKZONA INCORPORATED (US) | 1980-11-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170315031-A1 | TISSUE AND CELL STAIN FORMULA WITH A NOVEL MOLECULE OBTAINED FROM PAPAVER RHOEAS | MYADM, PRSS8, MKI67 | THRB 3702/4885POLB 927/4885MEN1 3419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.