Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | GRK2 | P25098 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | PLEC | Q15149 | 1/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.47 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.47 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396086 | 1.00 | MEN1 (0.70) | MEN1POLBGRK2KMT2APLEC | |
| SCHEMBL29538678 | 0.94 | POLB (0.66) | MEN1POLBGRK2KMT2APLEC | |
| SCHEMBL11791659 | 0.94 | MEN1 (0.66) | MEN1POLBGRK2KMT2APLEC | |
| SCHEMBL11791648 | 0.94 | MEN1 (0.66) | MEN1POLBGRK2KMT2APLEC | |
| SCHEMBL5859446 | 0.94 | POLB (0.66) | MEN1POLBGRK2KMT2APLEC | |
| SCHEMBL287038 | 0.94 | POLB (0.66) | MEN1POLBGRK2KMT2APLEC | |
| SCHEMBL29355238 | 0.93 | MEN1 (0.65) | MEN1POLBGRK2KMT2APLEC | |
| SCHEMBL590957 | 0.90 | MEN1 (0.61) | MEN1POLBGRK2KMT2APLEC | |
| SCHEMBL29833871 | 0.90 | MEN1 (0.61) | MEN1POLBGRK2KMT2APLEC | |
| SCHEMBL5859497 | 0.90 | MEN1 (0.61) | MEN1POLBGRK2KMT2APLEC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022122659-A1 | FREE-FLOW ELECTROPHORESIS METHOD FOR SEPARATING ANALYTES | WEBER GERHARD (DE) | 2022-06-16 | — | — | WO | disclosed |
| EP-4012395-A1 | FREE-FLOW ELECTROPHORESIS METHOD FOR SEPARATING ANALYTES | Weber, Gerhard (DE) | 2022-06-15 | — | — | EP | disclosed |
| US-10067089-B2 | Free-flow electrophoresis method for separating analytes | FFE SERVICE GMBH (DE) | 2018-09-04 | — | — | US | disclosed |
| US-20160238560-A1 | FREE-FLOW ELECTROPHORESIS METHOD FOR SEPARATING ANALYTES | FFE SERVICE GMBH (DE) | 2016-08-18 | — | — | US | disclosed |
| EP-3017297-A1 | FREE-FLOW ELECTROPHORESIS METHOD FOR SEPARATING ANALYTES | FFE Service GmbH (DE) | 2016-05-11 | — | — | EP | disclosed |
| WO-2015000600-A1 | FREE-FLOW ELECTROPHORESIS METHOD FOR SEPARATING ANALYTES | FFE SERVICE GMBH (DE) | 2015-01-08 | — | — | WO | disclosed |
| EP-2821781-A1 | Free-flow electrophoresis method for separating analytes | FFE Service GmbH (DE) | 2015-01-07 | — | — | EP | disclosed |
| US-20020015858-A1 | Optical recording medium and composition used for recording layer thereof | TOYO INK MFG. CO., LTD. (JP) | 2002-02-07 | — | — | US | disclosed |
| US-5397710-A | Fixing complexometric dye, metal mask, chelate compound alkaline buffer, and stabilizer on bibulous material covered with semipermeable membrane | DAVID DIAGNOSTICS, INC. (US) | 1995-03-14 | — | — | US | disclosed |
| WO-1993008684-A1 | PROCESS AND DEVICE FOR MEASURING MAGNESIUM IN BIOLOGICAL FLUIDS AND METHOD OF PREPARING THE DEVICE | STEINMAN GARY D (US) | 1993-05-13 | — | — | WO | disclosed |