Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469660 | 0.86 | MAOA (0.49) | CA12CA1CA2CA7CA13 | |
| SCHEMBL5376886 | 0.85 | MAOA (0.43) | MAOAMAOBARSLC2A1SOAT1 | |
| SCHEMBL9241946 | 0.83 | THRA (0.45) | MAOAMAOBARSLC2A1SOAT1 | |
| SCHEMBL9243196 | 0.83 | THRA (0.45) | MAOAMAOBARSLC2A1SOAT1 | |
| SCHEMBL7281456 | 0.83 | THRA (0.45) | MAOAMAOBARSLC2A1SOAT1 | |
| SCHEMBL11223570 | 0.83 | THRA (0.45) | MAOAMAOBARSLC2A1SOAT1 | |
| SCHEMBL5376643 | 0.83 | THRA (0.45) | MAOAMAOBARSLC2A1SOAT1 | |
| SCHEMBL11483343 | 0.83 | THRA (0.45) | MAOAMAOBARSLC2A1SOAT1 | |
| SCHEMBL7272059 | 0.83 | THRA (0.45) | MAOAMAOBARSLC2A1SOAT1 | |
| SCHEMBL13397872 | 0.82 | CA12 (0.61) | CA12CA1CA2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141391-B | Ethylene-polar styrene quasi-random copolymer and preparation method thereof | 中国科学院长春应用化学研究所 | 2020-03-13 | — | — | CN | claimed |
| US-7402589-B2 | Tri-substituted ureas as cytokine inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2008-07-22 | — | — | US | claimed |
| EP-1737830-A1 | TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS | The Procter and Gamble Company (US) | 2007-01-03 | — | — | EP | claimed |
| WO-2005105757-A1 | TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2005-11-10 | — | — | WO | claimed |
| US-20050245555-A1 | Tri-substituted ureas as cytokine inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2005-11-03 | — | — | US | claimed |
| CN-112912449-B | Composition for forming hard coat layer, hard coat layer using same, and laminate comprising same | 株式会社东进世美肯 | 2023-06-30 | — | — | CN | disclosed |
| US-11142495-B2 | Composition and method for manufacturing device using same | TOYO GOSEI CO., LTD. (JP) | 2021-10-12 | — | — | US | disclosed |
| CN-107141391-B | Ethylene-polar styrene quasi-random copolymer and preparation method thereof | 中国科学院长春应用化学研究所 | 2020-03-13 | — | — | CN | disclosed |
| US-20200048191-A1 | COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME | TOYO GOSEI CO., LTD. (JP) | 2020-02-13 | — | — | US | disclosed |
| CN-109843853-A | The manufacturing method of composition and the equipment using the composition | 东洋合成工业株式会社 | 2019-06-04 | — | — | CN | disclosed |
| EP-3098226-B1 | BORATE-BASED BASE GENERATOR, AND BASE-REACTIVE COMPOSITION COMPRISING SUCH BASE GENERATOR | FUJIFILM WAKO PURE CHEMICAL CORP (JP) | 2018-12-12 | — | — | EP | disclosed |
| US-10100070-B2 | Borate-based base generator, and base-reactive composition comprising such base generator | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2018-10-16 | — | — | US | disclosed |
| EP-0173126-A1 | Process for preparing novel dihydropyridine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| EP-0140352-A2 | Novel process for producing thiolsulfonic acid derivatives | Takeda Chemical Industries, Ltd. (JP) | 1985-05-08 | — | — | EP | disclosed |
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |
| EP-0004288-A2 | Phenoxyalkyl amines, pharmaceutical compositions containing them, and process for their preparation | MERCK PATENT GmbH (DE) | 1979-10-03 | — | — | EP | disclosed |
| US-4120886-A | APHIDICIDES | PPG INDUSTRIES, INC. (US) | 1978-10-17 | — | — | US | disclosed |
| US-4055656-A | S-ARYL-N-CYCLOALKYLTHIOLCARBAMATES | PPG INDUSTRIES, INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3971825-A | (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS | SANKYO COMPANY LIMITED (JA) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245555-A1 | Tri-substituted ureas as cytokine inhibitors | IL1B, IL1A, IL6 | CA12 3132/4885CA1 854/4885CA2 1280/4885 |
| US-10100070-B2 | Borate-based base generator, and base-reactive composition comprising such base generator | BLM, HPRT1, BROX | CA12 212/4885CA1 356/4885CA2 596/4885 |
| US-20200048191-A1 | COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME | LBR, LMTK2, MMS19 | CA12 4239/4885CA1 3890/4885CA2 1879/4885 |
| US-11142495-B2 | Composition and method for manufacturing device using same | LBR, LMTK2, MMS19 | CA12 4239/4885CA1 3890/4885CA2 1879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.