Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819187 | 0.86 | KDM4E (0.52) | SIRT1ALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL28819184 | 0.84 | SIRT1 (0.48) | SIRT1ALDH1A1HPGDCSF1RLMNA | |
| SCHEMBL14865005 | 0.84 | ALOX5 (0.56) | SIRT1ALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL28819202 | 0.83 | ALDH1A1 (0.64) | SIRT1ALDH1A1HPGDCYP1A2LMNA | |
| SCHEMBL8296306 | 0.81 | PRSS1 (0.55) | SIRT1ALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL28819201 | 0.80 | KDM4E (0.58) | ALDH1A1HPGDCYP1A2CYP2C19LMNA | |
| SCHEMBL4077176 | 0.78 | ALDH1A1 (0.69) | ALDH1A1HPGDCYP1A2XBP1CYP2C19 | |
| Methane SCHEMBL28638234 | 0.77 | ALOX15 (0.50) | ALDH1A1HPGDCYP1A2XBP1CYP2C19 | |
| SCHEMBL28819188 | 0.76 | GABRA1 (0.59) | ALDH1A1HPGDCYP1A2ALOX5LMNA | |
| SCHEMBL23803099 | 0.76 | RAB9A (0.50) | SIRT1ALDH1A1HPGDLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031541-B | Preparation method of 2-substituted 3-methylindole derivative | 太原理工大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-114031541-A | Preparation method of 2-substituted 3-methylindole derivative | 太原理工大学 | 2022-02-11 | — | — | CN | disclosed |