Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82746 | 0.85 | RORC (0.52) | RORCBCHEACHEBACE1ALDH1A1 | |
| SCHEMBL28824752 | 0.84 | SIGMAR1 (0.50) | RORCOPRM1BCHEACHEBACE1 | |
| SCHEMBL28824744 | 0.83 | OPRM1 (0.44) | OPRM1MAPTCYP3A4CYP2D6MAPK1 | |
| SCHEMBL2047049 | 0.81 | HTR1A (0.49) | RORCDRD2DRD3OPRM1BCHE | |
| SCHEMBL28824755 | 0.79 | LMNA (0.51) | BCHEACHEBACE1ALDH1A1MAPT | |
| SCHEMBL28824750 | 0.79 | OPRM1 (0.44) | OPRM1MAPTKDM1AMEN1KMT2A | |
| SCHEMBL11776123 | 0.77 | RORC (0.43) | RORCDRD2DRD1DRD3BCHE | |
| SCHEMBL6042431 | 0.76 | CFB (0.47) | RORCALDH1A1MAPTCYP3A4CYP2D6 | |
| SCHEMBL28824742 | 0.72 | RORC (0.52) | RORCALDH1A1KDM1AMEN1KMT2A | |
| SCHEMBL20148958 | 0.72 | ACHE (0.60) | RORCBCHEACHEBACE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114941145-B | Synthesis method of aziridine derivatives | 天津理工大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-114941145-A | Synthetic method of aziridine derivative | 天津理工大学 | 2022-08-26 | — | — | CN | disclosed |