Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824744 | 0.84 | OPRM1 (0.44) | SIGMAR1OPRM1MAPT | |
| SCHEMBL28824734 | 0.84 | RORC (0.52) | RORCMEN1KMT2AOPRM1ALDH1A1 | |
| SCHEMBL23064641 | 0.80 | DRD2 (0.54) | SIGMAR1RORCMEN1KMT2AOPRM1 | |
| SCHEMBL28824750 | 0.80 | OPRM1 (0.44) | SIGMAR1MEN1KMT2AOPRM1KDM1A | |
| SCHEMBL28824755 | 0.80 | LMNA (0.51) | SIGMAR1MEN1KMT2AALDH1A1BCHE | |
| SCHEMBL7107798 | 0.79 | TP53 (0.58) | SIGMAR1RORCMEN1KMT2AALDH1A1 | |
| SCHEMBL31612476 | 0.77 | SIGMAR1 (0.45) | SIGMAR1RORCMEN1KMT2AALDH1A1 | |
| SCHEMBL6497571 | 0.76 | CFB (0.47) | SIGMAR1RORCMEN1KMT2AALDH1A1 | |
| SCHEMBL11708798 | 0.76 | MEN1 (0.43) | SIGMAR1RORCMEN1KMT2AOPRM1 | |
| SCHEMBL13891233 | 0.75 | PRKCZ (0.45) | DRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114941145-B | Synthesis method of aziridine derivatives | 天津理工大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-114941145-A | Synthetic method of aziridine derivative | 天津理工大学 | 2022-08-26 | — | — | CN | disclosed |