SCHEMBL2887963

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5318161	0.78	L3MBTL1 (0.46)	MEN1KMT2AICAM1DHFRNPC1
	SCHEMBL2888693	0.75	GABRA1 (0.41)	LMNANSD2SLC6A2SLC6A4DHFR
	SCHEMBL30389926	0.74	GABRA1 (0.48)	LMNASLC6A2ITGB2ICAM1ITGAL
	SCHEMBL4808650	0.74	GABRA1 (0.48)	LMNASLC6A2ITGB2ICAM1ITGAL
	SCHEMBL5313607	0.73	CYP2C9 (0.51)	MEN1LMNAKMT2ASLC6A2DHFR
	SCHEMBL14113377	0.73	SLC6A4 (0.50)	MEN1LMNAKMT2ASLC6A4DHFR
	SCHEMBL4801714	0.70	MMP2 (0.52)	MEN1KMT2ADHFR
	SCHEMBL4800273	0.70	HTR1A (0.41)	LMNASLC6A2ITGB2ICAM1ITGAL
	SCHEMBL191108	0.69	ITGB2 (0.39)	LMNAITGB2ICAM1ITGAL
	SCHEMBL14959711	0.68	USP1 (0.52)	USP1WDR48NPC1RAB9AGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.