SCHEMBL28930366

SCHEMBL28930366

CCc1c(N(CC)CC)ccc(C)c1C

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 1/20 0.33
S100B P04271 1/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31
PSMD14 O00487 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
RECQL P46063 1/20 0.30
GFER P55789 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CRHR1 P34998 3/20 0.30
ALDH3A1 P30838 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27555107 0.80 S100B (0.36) ALDH1A3S100BALDH1A1GAAMAPT
SCHEMBL27673462 0.75 NR3C1 (0.36) S100BALDH1A1GAAMAPTNOS3
SCHEMBL3456090 0.74 NOS2 (0.43) NOS3NOS2TSHR
SCHEMBL395141 0.72 ALDH1A3 (0.38) ALDH1A3ALDH1A1GAAMAPTPSMD14
SCHEMBL2954428 0.71 NOS2 (0.42) S100BALDH1A1MAPTNOS3NOS2
SCHEMBL2270836 0.71 ALDH1A3 (0.33) ALDH1A3ALDH1A1GAAMAPTPSMD14
SCHEMBL4300630 0.70 TRPA1 (0.39) S100BALDH1A1MAPTCYP3A4TSHR
SCHEMBL5681241 0.69 ALDH1A1 (0.35) ALDH1A3ALDH1A1GAAMAPTCYP3A4
SCHEMBL29373928 0.69 TDP2 (0.34) ALDH1A1MAPTNOS3NOS2TSHR
SCHEMBL1086573 0.69 TDP2 (0.34) ALDH1A1MAPTNOS3NOS2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113813982-A Integral N-modified TS-1 catalyst carrier and preparation method thereof 华东理工大学 2021-12-21 CN claimed
CN-113813982-A Integral N-modified TS-1 catalyst carrier and preparation method thereof 华东理工大学 2021-12-21 CN disclosed