Uracil

Uracil

SCHEMBL2895224

CC(=O)[O-].CC(=O)[O-].O=c1cc[nH]c(=O)[nH]1.[Na+].[Na+]

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Uracil. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 1/20 0.68
▸ MMP2 P08253 1/20 0.43
▸ TP53 P04637 1/20 0.42
▸ CA1 P00915 3/20 0.36
▸ CYP1A2 P05177 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ PDE3B Q13370 1/20 0.31
▸ PDE3A Q14432 1/20 0.31
▸ TYMP P19971 1/20 0.31
▸ GSK3B P49841 1/20 0.31
▸ BACE1 P56817 1/20 0.31
▸ MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uracil SCHEMBL27495406 1.00 CRBN (0.68) CRBNMMP2TP53CA1CYP1A2
Uracil SCHEMBL27509565 1.00 CRBN (0.68) CRBNMMP2TP53CA1CYP1A2
Uracil SCHEMBL479740 0.88 CRBN (0.74) CRBNMMP2TP53CA1CYP1A2
Uracil SCHEMBL2895220 0.86 CRBN (0.71) CRBNMMP2TP53CA1CYP1A2
Uracil SCHEMBL3798527 0.82 CRBN (1.00) CRBNMMP2TP53CA1ALDH1A1
Uracil SCHEMBL8235 0.82 — —
Uracil SCHEMBL5089507 0.82 — —
Uracil SCHEMBL9429688 0.81 CRBN (0.77) CRBNMMP2TP53CYP1A2ALDH1A1
Uracil SCHEMBL25208560 0.81 CRBN (0.63) CRBNMMP2TP53CYP1A2ALDH1A1
Uracil SCHEMBL4664232 0.80 CRBN (0.94) CRBNMMP2TP53CA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060245-A Antistatic resin composition 东邦化学工业株式会社 2026-05-19 — — CN disclosed
EP-4722292-A1 YELLOW-AZO-PIGMENT-CONTAINING COLORING COMPOSITION AND METHOD FOR PRODUCING SAME Otsuka Chemical Co., Ltd. (JP) 2026-04-08 — — EP disclosed
US-12577421-B2 Inkjet ink, ink set, ink medium set, and printing medium NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2026-03-17 — — US disclosed
US-12552952-B2 Inkjet ink, inkjet recording method, ink set, ink medium set, and print medium NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2026-02-17 — — US disclosed
EP-4692255-A1 AQUEOUS INK COMPOSITION, INK SET, AND METHOD FOR PRODUCING INKJET-PRINTED MATTER Nippon Kayaku Kabushiki Kaisha (JP) 2026-02-11 — — EP disclosed
EP-4570873-A1 INKJET INK, INK SET, INK MEDIUM SET, AND PRINTING MEDIUM Nippon Kayaku Kabushiki Kaisha (JP) 2025-06-18 — — EP disclosed
CN-116997616-B Ink set, ink jet recording method, ink medium set, and printing medium 日本化药株式会社 2025-06-10 — — CN disclosed
US-20250179318-A1 INKJET INK NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-06-05 — — US disclosed
CN-116137841-B Coloring dispersion for inkjet, ink for inkjet recording, and inkjet recording method 日本化药株式会社 2025-04-25 — — CN disclosed
EP-4502086-A1 INKJET INK Nippon Kayaku Kabushiki Kaisha (JP) 2025-02-05 — — EP disclosed
EP-3950859-A1 COLORED DISPERSION, RECORDING MEDIUM, AND HYDROPHOBIC FIBER PRINTING METHOD Nippon Kayaku Kabushiki Kaisha (JP) 2022-02-09 — — EP disclosed
WO-2022025166-A1 COLORED DISPERSION FOR INKJET, INKJET RECORDING INK, AND INKJET RECORDING METHOD 日本化薬株式会社 2022-02-03 — — WO disclosed
WO-2022025034-A1 COLORED FLUID, INK SET, RECORDING MEDIUM, AND TEXTILE PRINTING METHOD FOR HYDROPHOBIC FIBERS 日本化薬株式会社 2022-02-03 — — WO disclosed
EP-2235122-B1 MAGENTA RECORDING INK COMPOSITION, INKJET RECORDING METHOD, AND INK RECORDED MATTER RICOH CO LTD (JP) 2015-08-26 — — EP disclosed
CN-101925661-B Magenta recording ink composition, ink jet recording method and ink recorded matter RICOH KK 2013-09-25 — — CN disclosed
US-8523992-B2 Magenta recording ink composition, inkjet recording method, and ink recorded matter RICOH COMPANY, LTD. (JP) 2013-09-03 — — US disclosed
CN-101925661-A Magenta recording ink composition, ink jet recording method and ink recorded matter RICOH KK 2010-12-22 — — CN disclosed
US-20100285287-A1 MAGENTA RECORDING INK COMPOSITION, INKJET RECORDING METHOD, AND INK RECORDED MATTER RICOH COMPANY, LTD. (JP) 2010-11-11 — — US disclosed
EP-2235122-A1 MAGENTA RECORDING INK COMPOSITION, INKJET RECORDING METHOD, AND INK RECORDED MATTER Ricoh Company, Ltd. (JP) 2010-10-06 — — EP disclosed
WO-2009093721-A1 MAGENTA RECORDING INK COMPOSITION, INKJET RECORDING METHOD, AND INK RECORDED MATTER RICOH COMPANY, LTD. (JP) 2009-07-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552952-B2 Inkjet ink, inkjet recording method, ink set, ink medium set, and print medium BMP1, SMAD2, SMAD3 CRBN 916/4885MMP2 1628/4885TP53 105/4885
US-12577421-B2 Inkjet ink, ink set, ink medium set, and printing medium MITF, EYA3, EYA2 CRBN 1048/4885MMP2 2219/4885TP53 409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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