Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 8/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 4/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.46 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Asparagine SCHEMBL30131205 | 1.00 | — | — | |
| Asparagine SCHEMBL8827 | 1.00 | — | — | |
| Asparagine SCHEMBL30486685 | 1.00 | — | — | |
| Asparagine SCHEMBL288094 | 1.00 | ALOX15 (0.56) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL288093 | 1.00 | ALOX15 (0.56) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL4347082 | 1.00 | ALOX15 (0.56) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL15460 | 1.00 | ALOX15 (0.56) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL8826 | 1.00 | — | — | |
| Asparagine SCHEMBL150535 | 1.00 | ALOX15 (0.56) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL20489207 | 1.00 | ALOX15 (0.56) | ALOX15BLMPMP22KMT2AGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 591 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017481-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2018-07-10 | — | — | US | claimed |
| EP-2836485-B1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2018-01-10 | — | — | EP | claimed |
| EP-2499148-B1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2017-01-18 | — | — | EP | claimed |
| US-9512139-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2016-12-06 | — | — | US | claimed |
| US-20150051183-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2015-02-19 | — | — | US | claimed |
| EP-2836485-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | Polyphor Ag (CH) | 2015-02-18 | — | — | EP | claimed |
| WO-2013139697-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2013-09-26 | — | — | WO | claimed |
| US-20120270881-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2012-10-25 | — | — | US | claimed |
| EP-2499148-A2 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | Polyphor Ag (CH) | 2012-09-19 | — | — | EP | claimed |
| CN-101531699-B | Polypeptide solid-state reaction method | KUNMING JIDA PHARMACEUTICAL CO., LTD. (CN) | 2012-02-15 | — | — | CN | claimed |
| US-5206014-A | Activating antibody response | SCLAVO, S.P.A. (IT) | 1993-04-27 | — | — | US | claimed |
| EP-0434675-A1 | POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY. | EASTMAN KODAK CO (US) | 1991-07-03 | — | — | EP | claimed |
| EP-0231728-B1 | SYNTHETIC PEPTIDE WITH HUMAN INTERLEUKIN 1 ACTIVITY | SCLAVO S.p.A. (IT) | 1991-05-22 | — | — | EP | claimed |
| EP-0417165-A1 | POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY. | EASTMAN KODAK CO (US) | 1991-03-20 | — | — | EP | claimed |
| EP-0400051-A1 | POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY. | EASTMAN KODAK CO (US) | 1990-12-05 | — | — | EP | claimed |
| WO-1989010933-A1 | POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | EASTMAN KODAK COMPANY (US) | 1989-11-16 | — | — | WO | claimed |
| WO-1989007110-A1 | POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | EASTMAN KODAK COMPANY (US) | 1989-08-10 | — | — | WO | claimed |
| WO-1988009780-A2 | POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | EASTMAN KODAK COMPANY (US) | 1988-12-15 | — | — | WO | claimed |
| EP-0293333-A2 | A synthetic nonapeptide of use as an adjuvant | SCLAVO S.p.A. (IT) | 1988-11-30 | — | — | EP | claimed |
| EP-0231728-A2 | Synthetic peptide with human interleukin 1 activity | SCLAVO S.p.A. (IT) | 1987-08-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10017481-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | CTSE, CTSB, CTSS | ALOX15 355/4885BLM 3021/4885PMP22 4263/4885 |
| US-20120270881-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | KCNB1, KCNAB1, KCNMB1 | ALOX15 4319/4885BLM 2382/4885PMP22 2272/4885 |
| US-20150051183-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | CTSE, CTSB, CTSS | ALOX15 355/4885BLM 3021/4885PMP22 4263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.