Sugi Predict

Sugi Predict / Compounds / SCHEMBL289737

SCHEMBL289737

SCHEMBL289737

CC(C)(C)P(c1cc2ccccc2n1-c1ccccc1)C(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.47
▸ TSHR P16473 1/20 0.47
▸ KDM4E B2RXH2 3/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ CYP19A1 P11511 2/20 0.38
▸ ATM Q13315 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ PLA2G10 O15496 3/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ SLC22A12 Q96S37 1/20 0.35
▸ CYP11B1 P15538 1/20 0.35
▸ CYP11B2 P19099 1/20 0.35
▸ MCL1 Q07820 1/20 0.34
▸ NOTUM Q6P988 1/20 0.34
▸ APP P05067 1/20 0.34
▸ HAO1 Q9UJM8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29593075 1.00 ALDH1A1 (0.47) ALDH1A1TSHRKDM4EMAPK1HTT
SCHEMBL16449100 0.80 ALDH1A1 (0.51) ALDH1A1TSHRKDM4EMAPK1HTT
SCHEMBL4345130 0.75 ALDH1A1 (0.39) ALDH1A1TSHRKDM4EHTTHPGD
SCHEMBL15447623 0.75 ALDH1A1 (0.50) ALDH1A1TSHRKDM4EMAPK1HTT
SCHEMBL12260645 0.75 ALDH1A1 (0.50) ALDH1A1TSHRKDM4EMAPK1HTT
SCHEMBL30388218 0.72 ALDH1A1 (0.47) ALDH1A1TSHRKDM4EMAPK1HTT
SCHEMBL20399835 0.72 ALDH1A1 (0.47) ALDH1A1TSHRKDM4EMAPK1HTT
SCHEMBL30446730 0.72 ALDH1A1 (0.55) ALDH1A1TSHRKDM4EMAPK1HTT
SCHEMBL1885602 0.72 ALDH1A1 (0.55) ALDH1A1TSHRKDM4EMAPK1HTT
SCHEMBL13425019 0.69 ALDH1A1 (0.43) ALDH1A1TSHRKDM4EMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2427468-B2 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PLC (GB) 2025-06-04 — — EP claimed
EP-4267591-A2 ORGANOMETALLIC COMPOUNDS Umicore AG & Co. KG (DE) 2023-11-01 — — EP claimed
CN-116802187-A Organometallic compounds 优米科尔股份公司及两合公司 2023-09-22 — — CN claimed
CN-114957312-A Aryl silicon compound of conjugated olefin and preparation method and application thereof 南京工业大学 2022-08-30 — — CN claimed
WO-2022136049-A2 ORGANOMETALLIC COMPOUNDS UMICORE AG & CO. KG (DE) 2022-06-30 — — WO claimed
EP-2427468-B1 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PLC (GB) 2017-06-14 — — EP claimed
CN-103917522-B Process for producing N- (hetero) arylazoles 高砂香料工业株式会社 2016-06-15 — — CN claimed
US-9233922-B2 Process for producing N-(hetero)arylazoles TAKASAGO INTERNATIONAL CORPORATION (JP) 2016-01-12 — — US claimed
US-8772520-B2 Preparation of a metal complex JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2014-07-08 — — US claimed
US-8314232-B2 Preparation of a quinolinyloxydiphenylcyclopropanedicarboxamide GLAXOSMITHKLINE LLC (US) 2012-11-20 — — US claimed
US-20120116109-A1 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2012-05-10 — — US claimed
EP-2427468-A1 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2012-03-14 — — EP claimed
WO-2010128316-A1 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2010-11-11 — — WO claimed
US-20100081805-A1 Preparation of a Quinolinyloxydiphenylcyclopropanedicarboxamide EXELIXIS, INC. 2010-04-01 — — US claimed
US-12503442-B2 Phenyl-3,4-dihydroisoquinolin-2(1h)-yl-ethan-1-one derivatives as dopamine d1receptor positive allosteric modulators ELI LILLY AND COMPANY (US) 2025-12-23 — — US disclosed
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES BHATTACHARYA SHRABANTI (US) 2025-12-04 — — US disclosed
US-20250197353-A1 METHOD OF FORMING BOND BY COUPLING REACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-06-19 — — US disclosed
WO-2010012650-A1 COMPOUNDS FOR THE TREATMENT OF METABOLIC DISEASES SYDDANSK UNIVERSITET (DK) 2010-02-04 — — WO disclosed
US-20090264434-A1 PYRIDAZINONE GLUCOKINASE ACTIVATORS BERTHEL STEVEN JOSEPH 2009-10-22 — — US disclosed
WO-2009127544-A1 PYRIDAZINONE GLUCOKINASE ACTIVATORS F. HOFFMANN-LA ROCHE AG (CH) 2009-10-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES CA4, CA12, CA14 ALDH1A1 688/4885TSHR 4615/4885KDM4E 500/4885
US-12503442-B2 Phenyl-3,4-dihydroisoquinolin-2(1h)-yl-ethan-1-one derivatives as dopamine d1receptor positive allosteric modulators HTR1D, ADRA1D, HTR1A ALDH1A1 814/4885TSHR 1105/4885KDM4E 1750/4885
US-20090264434-A1 PYRIDAZINONE GLUCOKINASE ACTIVATORS GCK, GCKR, PDXK ALDH1A1 1059/4885TSHR 2033/4885KDM4E 2578/4885
US-20120116109-A1 PREPARATION OF A METAL COMPLEX PDCD1LG2, CD274, PDCD2L ALDH1A1 4059/4885TSHR 1075/4885KDM4E 2792/4885
US-20250197353-A1 METHOD OF FORMING BOND BY COUPLING REACTION CBR1, CBR3, NOX4 ALDH1A1 1855/4885TSHR 1022/4885KDM4E 1306/4885
US-20100081805-A1 Preparation of a Quinolinyloxydiphenylcyclopropanedicarboxamide QDPR, CBR3, NQO2 ALDH1A1 736/4885TSHR 1074/4885KDM4E 1032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.