Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 5/20 | 0.37 |
| ▸ | MMP1 | P03956 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193620 | 0.83 | MMP13 (0.38) | MMP13MMP1BLMMMP2MMP3 | |
| SCHEMBL29659094 | 0.78 | MMP13 (0.33) | MMP13MMP1 | |
| SCHEMBL14827913 | 0.78 | MMP13 (0.34) | MMP13MMP1 | |
| SCHEMBL29697284 | 0.77 | MMP1 (0.33) | MMP13MMP1 | |
| SCHEMBL29697290 | 0.76 | TP53 (0.40) | MMP13MMP1SMN1; SMN2 | |
| SCHEMBL29697248 | 0.75 | PMP22 (0.35) | MMP13MMP1 | |
| SCHEMBL25251069 | 0.75 | P2RX7 (0.39) | GAA | |
| SCHEMBL29697309 | 0.74 | PTGES (0.35) | MMP13MMP1ALDH1A1HTT | |
| SCHEMBL1132391 | 0.72 | — | — | |
| SCHEMBL12236182 | 0.70 | APEX1 (0.33) | APEX1BLMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |