SCHEMBL29697248

SCHEMBL29697248

CS(=N)(=O)CCN1CC(C(N)=O)NC1=O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PMP22 Q01453 1/20 0.35
MMP1 P03956 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29697284 0.88 MMP1 (0.33) MMP1MMP13
SCHEMBL29697309 0.79 PTGES (0.35) MMP1MMP13
SCHEMBL29005236 0.75 MMP13 (0.37) MMP1MMP13
SCHEMBL29659094 0.75 MMP13 (0.33) MMP1MMP13
SCHEMBL29697297 0.70 GLI1 (0.32)
SCHEMBL25251069 0.69 P2RX7 (0.39)
SCHEMBL29697290 0.67 TP53 (0.40) MMP1MMP13
SCHEMBL12236182 0.65 APEX1 (0.33)
SCHEMBL10818207 0.64 MMP13 (0.36) MMP1MMP13
SCHEMBL8237994 0.62 POLB (0.41) MMP1MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4010080-A1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER Artios Pharma Limited (GB) 2022-06-15 EP disclosed