Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29005236 | 0.76 | MMP13 (0.37) | SMN1; SMN2MMP13MMP1 | |
| SCHEMBL11428909 | 0.73 | TP53 (0.45) | TP53HBBSMN1; SMN2DHFR | |
| SCHEMBL29659094 | 0.70 | MMP13 (0.33) | MMP13MMP1 | |
| SCHEMBL29697284 | 0.69 | MMP1 (0.33) | MMP13MMP1 | |
| SCHEMBL29697248 | 0.67 | PMP22 (0.35) | MMP13MMP1 | |
| SCHEMBL25251069 | 0.66 | P2RX7 (0.39) | — | |
| SCHEMBL29697309 | 0.66 | PTGES (0.35) | MMP13MMP1 | |
| SCHEMBL11598636 | 0.63 | TP53 (0.56) | TP53HBBSMN1; SMN2DHFR | |
| SCHEMBL3471790 | 0.63 | TP53 (0.56) | TP53HBBSMN1; SMN2DHFR | |
| SCHEMBL12236182 | 0.62 | APEX1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010080-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | Artios Pharma Limited (GB) | 2022-06-15 | — | — | EP | disclosed |