SCHEMBL2906295

SCHEMBL2906295

[CH2]CCOC(=O)Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.42
MAPT P10636 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
ATM Q13315 2/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
ALOX15 P16050 2/20 0.39
HSD17B10 Q99714 3/20 0.39
HPGD P15428 1/20 0.39
PKM P14618 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP19A1 P11511 1/20 0.39
MEN1 O00255 1/20 0.38
HTT P42858 1/20 0.38
GFER P55789 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2900757 0.89 TDP1 (0.43) THRBMAPTTDP1KDM4EL3MBTL1
SCHEMBL8646552 0.88 THRB (0.47) THRBMAPTTDP1KDM4EL3MBTL1
SCHEMBL304537 0.84 MAPT (0.43) THRBMAPTTDP1KDM4EL3MBTL1
SCHEMBL6754012 0.82 THRB (0.43) THRBMAPTTDP1KDM4EL3MBTL1
SCHEMBL8069407 0.82 MAPT (0.42) THRBMAPTTDP1KDM4EL3MBTL1
SCHEMBL288157 0.82 ALDH1A1 (0.52) THRBMAPTTDP1KDM4EL3MBTL1
SCHEMBL28670261 0.82 THRB (0.43) THRBMAPTTDP1KDM4EL3MBTL1
SCHEMBL16814873 0.82 TDP1 (0.52) TDP1L3MBTL1ALDH1A1
SCHEMBL6751546 0.82 THRB (0.43) THRBMAPTTDP1KDM4EL3MBTL1
Formaldehyde SCHEMBL28260770 0.81 LMNA (0.53) THRBMAPTMTNR1AMTNR1BHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108899-A Curable resin composition, cured product, and method for producing cured product 东京应化工业株式会社 2024-05-31 CN disclosed
CN-118109069-A Resin composition, cured product, and method for producing cured product 东京应化工业株式会社 2024-05-31 CN disclosed
EP-2217564-A1 COMPLEX PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE XenoPort, Inc. (US) 2010-08-18 EP disclosed
US-20090076147-A1 COMPLEX PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE XENOPORT, INC. 2009-03-19 US disclosed
WO-2009033054-A1 COMPLEX PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE XENOPORT, INC. (US) 2009-03-12 WO disclosed
US-5428138-A Colorfastness, washfastness, pH sensitivity CASSELLA AG (DE) 1995-06-27 US disclosed
EP-0391121-B1 Monoazo dyes, their preparation and use CASSELLA FARBWERKE MAINKUR AG (DE) 1994-11-23 EP disclosed
EP-0387642-B1 Mixture of dyes CASSELLA FARBWERKE MAINKUR AG (DE) 1994-07-27 EP disclosed
EP-0222255-B1 MIXTURES OF BLUE DISPERSE DYES AND THEIR USE IN DYEING POLYESTERS CASSELLA Aktiengesellschaft (DE) 1992-08-26 EP disclosed
US-RE33908-E Mixtures of blue mono-azo disperse dyestuffs and their use for dyeing polyester CASSELLA AKTIENGESELLSCHAFT (DE) 1992-05-05 US disclosed
US-5071443-A BLUE AZO DYESTUFF MIXTURE FOR STRONG BLUE COLOR ON HYDROPHOBIC FIBERS CASSELLA AKTIENGESELLSCHAFT (DE) 1991-12-10 US disclosed
EP-0391121-A1 Monoazo dyes, their preparation and use CASSELLA Aktiengesellschaft (DE) 1990-10-10 EP disclosed
EP-0387642-A2 Mixture of dyes CASSELLA Aktiengesellschaft (DE) 1990-09-19 EP disclosed
US-4678476-A HIGH TINCTORIAL STRENGTH, COLORFASTNESS CASSELLA AKTIENGESELLSCHAFT (DE) 1987-07-07 US disclosed
EP-0222255-A2 Mixtures of blue disperse dyes and their use in dyeing polyesters CASSELLA Aktiengesellschaft (DE) 1987-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090076147-A1 COMPLEX PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE ADSL, SLC19A1, SLC25A21 THRB 1698/4885MAPT 2379/4885TDP1 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.