Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6355702 | 1.00 | CYP1A2 (0.35) | CYP1A2 | |
| SCHEMBL16418243 | 0.85 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL121846 | 0.81 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL6563545 | 0.78 | CYP1A2 (0.32) | CYP1A2 | |
| SCHEMBL5390033 | 0.78 | TSHR (0.36) | — | |
| SCHEMBL583697 | 0.77 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL2357386 | 0.74 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL3409194 | 0.74 | CYP1A2 (0.34) | CYP1A2 | |
| SCHEMBL10964692 | 0.74 | CYP1A2 (0.34) | CYP1A2 | |
| SCHEMBL117857 | 0.73 | CYP1A2 (0.36) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494104-B1 | WARMING SENSATION COMPOUNDS | TAKASAGO PERFUMERY CO LTD (JP) | 2023-11-15 | — | — | EP | claimed |
| EP-3658109-B1 | COOLING AND FLAVOR BOOSTING COMPOSITIONS | FIRMENICH & CIE (CH) | 2022-12-07 | — | — | EP | claimed |
| US-11059771-B2 | Warming sensation compounds | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2021-07-13 | — | — | US | claimed |
| US-11034644-B2 | — | — | 2021-06-15 | — | — | US | claimed |
| US-20200306156-A1 | COOLING AND FLAVOR BOOSTING COMPOSITIONS | FIRMENICH SA (CH) | 2020-10-01 | — | — | US | claimed |
| US-20190169111-A1 | WARMING SENSATION COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2019-06-06 | — | — | US | claimed |
| EP-2810564-B1 | Sensation masking composition | TAKASAGO INT CORP (USA) (US) | 2017-06-14 | — | — | EP | claimed |
| US-20150327583-A1 | SENSATION MASKING COMPOSITION | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2015-11-19 | — | — | US | claimed |
| EP-1912516-B1 | SENSATION MASKING COMPOSITION | TAKASAGO INTERNAT CORP USA (US) | 2014-06-25 | — | — | EP | claimed |
| US-8377422-B2 | Carboxamide derivatives having cooling properties | GIVAUDAN S.A. (CH) | 2013-02-19 | — | — | US | claimed |
| EP-2167024-A2 | COOLING COMPOUNDS | Givaudan SA (CH) | 2010-03-31 | — | — | EP | claimed |
| US-20090275669-A1 | Flavor and fragrance composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-11-05 | — | — | US | claimed |
| US-20090035364-A1 | PARA-SUBSTITUTED 2-ALKOXYPHENOL COMPOUNDS | GIVAUDAN SA (CH) | 2009-02-05 | — | — | US | claimed |
| US-20080311232-A1 | Cooling Compounds | GIVAUDAN, SA (CH) | 2008-12-18 | — | — | US | claimed |
| WO-2008151460-A2 | COOLING COMPOUNDS | GIVAUDAN SA (CH) | 2008-12-18 | — | — | WO | claimed |
| US-20070225378-A1 | Menthol Dearivative and Cooling Agent Composition Comprising the Same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-09-27 | — | — | US | claimed |
| US-20070092623-A1 | Food products containing a fruit component | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-04-26 | — | — | US | claimed |
| US-20070036733-A1 | Sensation masking composition | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2007-02-15 | — | — | US | claimed |
| US-20060269500-A1 | Topical warming composition | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2006-11-30 | — | — | US | claimed |
| EP-1122233-B1 | A (1'R, 2'S, 5'R)-3-l-menthoxypropan-1-ol cooling sensate | TAKASAGO PERFUMERY CO LTD (JP) | 2004-01-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070036733-A1 | Sensation masking composition | TRPA1, TRPV1, TRPM5 | CYP1A2 1951/4885 |
| US-20060269500-A1 | Topical warming composition | CUTA, NACA, LSM14A | CYP1A2 1601/4885 |
| US-11059771-B2 | Warming sensation compounds | TRPA1, TRPV1, TRPV4 | CYP1A2 2350/4885 |
| US-20200306156-A1 | COOLING AND FLAVOR BOOSTING COMPOSITIONS | TAS2R20, TAS2R10, TAS2R40 | CYP1A2 3070/4885 |
| US-20150327583-A1 | SENSATION MASKING COMPOSITION | TRPA1, TRPV1, TRPM5 | CYP1A2 1951/4885 |
| US-20080311232-A1 | Cooling Compounds | MAL2, NCOR2, NCOA2 | CYP1A2 192/4885 |
| US-11034644-B2 | — | TRPA1, TRPV1, TRPV5 | CYP1A2 1960/4885 |
| US-20070225378-A1 | Menthol Dearivative and Cooling Agent Composition Comprising the Same | TRPM7, TRPA1, TRPM2 | CYP1A2 515/4885 |
| US-20190169111-A1 | WARMING SENSATION COMPOUNDS | TRPA1, TRPV1, TRPV4 | CYP1A2 2350/4885 |
| US-20090275669-A1 | Flavor and fragrance composition | TAS2R40, TAS2R1, TAS2R50 | CYP1A2 136/4885 |
| US-20090035364-A1 | PARA-SUBSTITUTED 2-ALKOXYPHENOL COMPOUNDS | EBP, CYP1A1, CYP2E1 | CYP1A2 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.