Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 2/20 | 0.42 |
| ▸ | ACLY | P53396 | 5/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | DCLRE1B | Q9H816 | 2/20 | 0.38 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137920 | 0.87 | AKR1C2 (0.42) | AKR1C2AKR1C1HNF4AACLYWDR5 | |
| SCHEMBL30209232 | 0.81 | WDR5 (0.44) | HNF4AACLYWDR5ACMSDDCLRE1B | |
| SCHEMBL16850337 | 0.77 | CES2 (0.42) | AKR1C2AKR1C1TTRACMSDALDH1A1 | |
| SCHEMBL28166374 | 0.76 | AKR1C2 (0.45) | AKR1C2AKR1C1HNF4AACLYWDR5 | |
| SCHEMBL332581 | 0.75 | ALDH1A1 (0.57) | HNF4AWDR5ACMSDDCLRE1BDCLRE1A | |
| SCHEMBL22190013 | 0.74 | ALDH1A1 (0.46) | HNF4AWDR5ACMSDDCLRE1BDCLRE1A | |
| SCHEMBL15057790 | 0.72 | MEN1 (0.50) | AKR1C2AKR1C1HNF4AACLYTTR | |
| SCHEMBL901069 | 0.72 | ACMSD (0.61) | HNF4AACLYWDR5ACMSDDCLRE1B | |
| SCHEMBL11691857 | 0.71 | FABP4 (0.43) | HNF4AWDR5ACMSDDCLRE1BDCLRE1A | |
| SCHEMBL12006684 | 0.71 | HNF4A (0.55) | AKR1C2AKR1C1HNF4AWDR5ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062804-A | 1, 3-substituted cyclobutyl derivatives and their use | 诺华股份有限公司 | 2023-11-14 | — | — | CN | disclosed |