Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 7/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 4/20 | 0.32 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.31 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3312128 | 0.73 | NPSR1 (0.35) | — | |
| SCHEMBL3313722 | 0.73 | NPSR1 (0.35) | — | |
| SCHEMBL3312135 | 0.73 | NPSR1 (0.35) | — | |
| SCHEMBL21941402 | 0.67 | CD44 (0.40) | CD44HTR2CHTR2BHTR2A | |
| SCHEMBL5527373 | 0.67 | OPRD1 (0.46) | — | |
| SCHEMBL2452095 | 0.66 | SIGMAR1 (0.33) | HTR2CHTR2BHTR2ABACE1 | |
| SCHEMBL22688968 | 0.66 | OPRM1 (0.38) | — | |
| SCHEMBL21619228 | 0.65 | HSD11B1 (0.39) | — | |
| SCHEMBL22978632 | 0.65 | RBP4 (0.42) | CD44HTR2CHTR2BHTR2ABACE1 | |
| SCHEMBL20162423 | 0.64 | PIM1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981661-A | Condensed ring substituted six-membered heterocyclic compound, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2023-10-31 | — | — | CN | disclosed |