Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932341 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTHTTLMNA | |
| SCHEMBL8079170 | 0.72 | HTT (0.55) | ALDH1A1KDM4EMAPTHTTLMNA | |
| SCHEMBL6939073 | 0.72 | POLB (0.46) | P2RX7ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL1147584 | 0.72 | NPC1 (0.41) | ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL194548 | 0.71 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTTDP1RAB9A | |
| SCHEMBL2926156 | 0.71 | P2RX7 (0.50) | P2RX7ALDH1A1LMNATDP1RAB9A | |
| SCHEMBL2363536 | 0.70 | P2RX7 (0.60) | P2RX7ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL16098187 | 0.70 | P2RX7 (0.60) | P2RX7ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL78126 | 0.68 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNATDP1RXFP1 | |
| SCHEMBL7171041 | 0.68 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNATDP1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732550-B2 | Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MITI (JP) | 2010-06-08 | — | — | US | disclosed |
| EP-0922715-B1 | Stimuli-responsive polymer utilizing keto-enol tautomerization | AGENCY IND SCIENCE TECHN (JP) | 2008-04-02 | — | — | EP | disclosed |
| US-6858694-B2 | Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY MITI (JP) | 2005-02-22 | — | — | US | disclosed |
| US-6852819-B2 | Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MITI (JP) | 2005-02-08 | — | — | US | disclosed |
| US-20040223947-A1 | Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same | JNC CORPORATION (JP) | 2004-11-11 | — | — | US | disclosed |
| US-20040223945-A1 | Stimuti-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same | JNC CORPORATION (JP) | 2004-11-11 | — | — | US | disclosed |
| US-20020188084-A1 | Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same | JNC CORPORATION (JP) | 2002-12-12 | — | — | US | disclosed |
| EP-0922715-A2 | Stimuli-responsive polymer utilizing keto-enol tautomerization | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY MITI (JP) | 1999-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040223945-A1 | Stimuti-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same | CREB1, STIM2, GABRE | P2RX7 4273/4885ALDH1A1 3954/4885KDM4E 1159/4885 |
| US-20040223947-A1 | Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same | ACMSD, ADSL, CREB1 | P2RX7 4804/4885ALDH1A1 3055/4885KDM4E 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.