Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of E110. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 1.00 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PTPRA | P18433 | 1/20 | 0.51 |
| ▸ | PTPRB | P23467 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E110 SCHEMBL323402 | 1.00 | THRB (1.00) | THRBCYP1A2CYP2C9PTPN1MAPT | |
| E110 SCHEMBL13276157 | 1.00 | THRB (1.00) | THRBCYP1A2CYP2C9PTPN1MAPT | |
| E110 SCHEMBL142458 | 1.00 | THRB (1.00) | THRBCYP1A2CYP2C9PTPN1MAPT | |
| SCHEMBL12760915 | 0.97 | THRB (0.95) | THRBCYP1A2CYP2C9PTPN1MAPT | |
| SCHEMBL3196947 | 0.93 | THRB (0.88) | THRBCYP1A2CYP2C9PTPN1MAPT | |
| SCHEMBL29489969 | 0.93 | THRB (0.88) | THRBCYP1A2CYP2C9PTPN1MAPT | |
| SCHEMBL4808237 | 0.93 | THRB (0.88) | THRBCYP1A2CYP2C9PTPN1MAPT | |
| SCHEMBL30341067 | 0.92 | THRB (0.85) | THRBCYP1A2CYP2C9PTPN1MAPT | |
| SCHEMBL9343017 | 0.92 | THRB (0.85) | THRBCYP1A2CYP2C9PTPN1MAPT | |
| SCHEMBL29394731 | 0.92 | THRB (0.85) | THRBCYP1A2CYP2C9PTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2691 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12636289-B2 | Lamotrigine oral liquid suspension and use thereof | OWP Pharmaceuticals, Inc. (US) | 2026-05-26 | — | — | US | claimed |
| US-12629377-B2 | Lamotrigine oral liquid suspension and use thereof | ROWP IP HOLDING II LLC | 2026-05-19 | — | — | US | claimed |
| WO-2026089857-A1 | METHOD OF PREPARING AND USING A SKIN CARE COMPOSITION | DOW SILICONES CORPORATION (US) | 2026-04-30 | — | — | WO | claimed |
| WO-2026089856-A1 | METHOD OF PREPARING AND USING A SKIN CARE FORMULATION | DOW SILICONES CORPORATION (US) | 2026-04-30 | — | — | WO | claimed |
| WO-2026087310-A1 | COMPOSITION, CONSUMABLE AND METHODS | GIVAUDAN SA (CH) | 2026-04-30 | — | — | WO | claimed |
| EP-4728588-A1 | COIN CELL BATTERIES WITH AVERSIVE-AGENT COATING | Energizer Brands, LLC (US) | 2026-04-22 | — | — | EP | claimed |
| EP-4728589-A1 | LITHIUM COIN CELL BATTERIES WITH POLYMER AND AVERSIVE-AGENT COATING LOCATED EXTERIOR TO THE CELL TO AVOID IMPACTING CONDUCTIVITY | Energizer Brands, LLC (US) | 2026-04-22 | — | — | EP | claimed |
| US-12599624-B2 | Biodegradable lung sealants | ETHICON, INC. (US) | 2026-04-14 | — | — | US | claimed |
| US-12594241-B2 | Topiramate oral liquid suspension and use thereof | OWP PHARMACEUTICALS INC (US) | 2026-04-07 | — | — | US | claimed |
| EP-4716527-A1 | A MULTIPLE UNIT ORAL DOSAGE FORM OF DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE FREE OF TITANIUM DIOXIDE | Italfarmaco SpA (IT) | 2026-04-01 | — | — | EP | claimed |
| CN-115003388-A | Aqueous sunscreen formulations based on sulfated crystalline cellulose SPF boosters | 陶氏环球技术有限责任公司 | 2022-09-02 | — | — | CN | claimed |
| WO-2022174078-A1 | PARTICLES CONTAINING COLORING AGENTS AND METHODS OF USING THE SAME | EPHEMERAL SOLUTIONS, INC. (US) | 2022-08-18 | — | — | WO | claimed |
| EP-3761947-B1 | LIPID MIXTURE OF STEARYL BEHENATE AND TRISTEARIN | BEIERSDORF AG (DE) | 2022-08-10 | — | — | EP | claimed |
| CN-114808488-A | Organic modified clay paste for direct dye printing of cotton fabrics and preparation method and application thereof | 武汉纺织大学 | 2022-07-29 | — | — | CN | claimed |
| US-20220193119-A1 | ANTISEPTIC SKIN PREP COMPOSITION | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2022-06-23 | — | — | US | claimed |
| EP-2883531-B1 | Bleaching and coloring composition for hair | KAO CORP (JP) | 2022-06-15 | — | — | EP | claimed |
| WO-2022066592-A1 | SKIN CARE FORMULATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-03-31 | — | — | WO | claimed |
| CN-114241438-A | Traffic signal lamp rapid and accurate identification method based on prior information | 电子科技大学 | 2022-03-25 | — | — | CN | claimed |
| US-20220079919-A1 | LISINOPRIL COMPOSITIONS WITH AN INGESTIBLE EVENT MARKER | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-03-17 | — | — | US | claimed |
| US-11234910-B2 | Capsules comprising pigments, and method for producing same | AMOREPACIFIC CORPORATION (KR) | 2022-02-01 | — | — | US | claimed |