Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.88 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PTPRA | P18433 | 1/20 | 0.57 |
| ▸ | PTPRB | P23467 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196947 | 1.00 | THRB (0.88) | THRBCYP1A2CYP2C9TSHRPTPRA | |
| SCHEMBL4808237 | 1.00 | THRB (0.88) | THRBCYP1A2CYP2C9TSHRPTPRA | |
| E110 SCHEMBL142458 | 0.93 | THRB (1.00) | THRBCYP1A2CYP2C9TSHRPTPRA | |
| E110 SCHEMBL13276157 | 0.93 | THRB (1.00) | THRBCYP1A2CYP2C9TSHRPTPRA | |
| E110 SCHEMBL29350765 | 0.93 | THRB (1.00) | THRBCYP1A2CYP2C9TSHRPTPRA | |
| E110 SCHEMBL323402 | 0.93 | THRB (1.00) | THRBCYP1A2CYP2C9TSHRPTPRA | |
| SCHEMBL30486026 | 0.93 | CYP1A2 (0.83) | THRBCYP1A2CYP2C9TSHRPTPRA | |
| SCHEMBL30940027 | 0.92 | CYP1A2 (0.85) | THRBCYP1A2CYP2C9TSHRPTPRA | |
| SCHEMBL628908 | 0.92 | CYP1A2 (0.85) | THRBCYP1A2CYP2C9TSHRPTPRA | |
| SCHEMBL112146 | 0.92 | CYP1A2 (0.85) | THRBCYP1A2CYP2C9TSHRPTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986979-A1 | DEFECT MEDIATED LYOTROPIC NEMATIC GEL | The University Court Of The University of Edinburgh (GB) | 2022-04-27 | — | — | EP | claimed |
| US-20250367330-A1 | OPTICAL CLEARING ENABLED BY THE KRAMERS-KRONIG RELATION | UNIV LELAND STANFORD JUNIOR (US) | 2025-12-04 | — | — | US | disclosed |
| CN-117736498-A | Colored organic peroxide compositions | 阿科玛股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-4298185-A1 | A SYSTEM COMPRISING A NEMATIC LIQUID CRYSTAL AND AN INTERFACE | The University Court Of The University of Edinburgh (GB) | 2024-01-03 | — | — | EP | disclosed |
| WO-2022238678-A1 | A SYSTEM COMPRISING A NEMATIC LIQUID CRYSTAL AND AN INTERFACE | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2022-11-17 | — | — | WO | disclosed |
| EP-4054523-A1 | ORALLY ADMINISTRABLE FILMS COMPRISING POORLY WATER SOLUBLE ACTIVE INGREDIENTS AND PREPARATION THEREOF | Maabarot Products Ltd. (IL) | 2022-09-14 | — | — | EP | disclosed |
| EP-3986979-A1 | DEFECT MEDIATED LYOTROPIC NEMATIC GEL | The University Court Of The University of Edinburgh (GB) | 2022-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250367330-A1 | OPTICAL CLEARING ENABLED BY THE KRAMERS-KRONIG RELATION | TNNC1, GYS1, MUSK | THRB 4429/4885CYP1A2 1361/4885CYP2C9 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.