SCHEMBL29358488

SCHEMBL29358488

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nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
LAP3 P28838 3/20 0.46
MEN1 O00255 1/20 0.45
LMNA P02545 1/20 0.45
KMT2A Q03164 1/20 0.45
MME P08473 3/20 0.43
MAPT P10636 1/20 0.43
ACE P12821 1/20 0.43
CPA1 P15085 1/20 0.43
ACE2 Q9BYF1 1/20 0.43
FOLH1 Q04609 2/20 0.41
PLA2G2A P14555 2/20 0.40
PLA2G5 P39877 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18766260 0.94 ALDH1A1 (0.53) ALDH1A1LAP3MEN1LMNAKMT2A
SCHEMBL3010038 0.94 ALDH1A1 (0.53) ALDH1A1LAP3MEN1LMNAKMT2A
SCHEMBL3010040 0.94 ALDH1A1 (0.53) ALDH1A1LAP3MEN1LMNAKMT2A
SCHEMBL29563014 0.94 ALDH1A1 (0.53) ALDH1A1LAP3MEN1LMNAKMT2A
SCHEMBL3402343 0.94 ALDH1A1 (0.53) ALDH1A1LAP3MEN1LMNAKMT2A
SCHEMBL28092553 0.92 ALDH1A1 (0.51) ALDH1A1LAP3MEN1LMNAKMT2A
SCHEMBL28092554 0.92 ALDH1A1 (0.51) ALDH1A1LAP3MEN1LMNAKMT2A
SCHEMBL16698433 0.91 ALDH1A1 (0.50) ALDH1A1LAP3MEN1LMNAKMT2A
SCHEMBL16698435 0.91 ALDH1A1 (0.50) ALDH1A1LAP3MEN1LMNAKMT2A
SCHEMBL29528227 0.88 ACE (0.50) ALDH1A1LAP3MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144882-A1 ANTI-NECTIN-4 ANTIBODY DRUG CONJUGATE AND USE THEREOF BIO-THERA SOLUTIONS, LTD. (CN) 2026-05-28 US claimed
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN INC (US) 2026-05-07 US claimed
US-20260008848-A1 ANTI-NECTIN-4 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF BIO THERA SOLUTIONS LTD (CN) 2026-01-08 US claimed
US-20250381283-A1 METHOD FOR TREATING SOLID TUMOR BIO THERA SOLUTIONS LTD (CN) 2025-12-18 US claimed
US-20250333498-A1 ANTI-CLDN18.2 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF BIO THERA SOLUTIONS LTD (CN) 2025-10-30 US claimed
US-20250262316-A1 ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF BIO-THERA SOLUTIONS, LTD. (CN) 2025-08-21 US claimed
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof IMMUNOGEN, INC. (US) 2025-08-19 US claimed
US-20250249114-A1 METHOD FOR TREATING HER2-POSITIVE SOLID TUMOR BIO-THERA SOLUTIONS, LTD. (CN) 2025-08-07 US claimed
EP-4556027-A1 ANTI-NECTIN-4 ANTIBODY DRUG CONJUGATE AND USE THEREOF Bio-Thera Solutions, Ltd. (CN) 2025-05-21 EP claimed
EP-4545099-A1 METHOD FOR TREATING SOLID TUMOR Bio-Thera Solutions, Ltd. (CN) 2025-04-30 EP claimed
US-20230094471-A1 CYTOTOXIC BIS-BENZODIAZEPINE DERIVATIVES AND CONJUGATES THEREOF WITH CELL-BINDING AGENTS FOR INHIBITING ABNORMAL CELL GROWTH OR FOR TREATING PROLIFERATIVE DISEASES IMMUNOGEN, INC. (US) 2023-03-30 US claimed
WO-2022253284-A1 DRUG CONJUGATE AND USE THEREOF 百奥泰生物制药股份有限公司 2022-12-08 WO claimed
US-20220372152-A1 ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF IMMUNOGEN, INC. 2022-11-24 US claimed
WO-2022192134-A1 METHODS FOR INCREASING EFFICACY OF IMMUNOCONJUGATES TARGETING ADAM9 FOR THE TREATMENT OF CANCER IMMUNOGEN, INC. (US) 2022-09-15 WO claimed
CN-106604927-B Cytotoxic benzodiazepine derivatives 伊缪诺金公司 2022-08-09 CN claimed
US-11332535-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IMMUNOGEN, INC. (US) 2022-05-17 US claimed
US-20220111067-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN SWITZERLAND GMBH (CH) 2022-04-14 US claimed
CN-114222756-A Biparatopic FR-alpha antibodies and immunoconjugates 伊缪诺金公司 2022-03-22 CN claimed
EP-3962935-A1 BIPARATOPIC FR-ALPHA ANTIBODIES AND IMMUNOCONJUGATES Immunogen, Inc. (US) 2022-03-09 EP claimed
EP-3941527-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES ImmunoGen, Inc. (US) 2022-01-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008848-A1 ANTI-NECTIN-4 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF NECTIN4, VSIG8, IGSF11 ALDH1A1 1734/4885LAP3 3241/4885MEN1 1693/4885
US-20250249114-A1 METHOD FOR TREATING HER2-POSITIVE SOLID TUMOR ERBB2, EGFR, ERBB3 ALDH1A1 3196/4885LAP3 341/4885MEN1 2613/4885
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof VIP, AREG, MIF ALDH1A1 1927/4885LAP3 960/4885MEN1 786/4885
US-20260144882-A1 ANTI-NECTIN-4 ANTIBODY DRUG CONJUGATE AND USE THEREOF NECTIN4, CD22, NGFR ALDH1A1 2339/4885LAP3 1173/4885MEN1 1105/4885
US-20220111067-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VIP, AREG, MIF ALDH1A1 1927/4885LAP3 960/4885MEN1 786/4885
US-20230094471-A1 CYTOTOXIC BIS-BENZODIAZEPINE DERIVATIVES AND CONJUGATES THEREOF WITH CELL-BINDING AGENTS FOR INHIBITING ABNORMAL CELL GROWTH OR FOR TREATING PROLIFERATIVE DISEASES GABBR2, GABRB1, GABRB2 ALDH1A1 1615/4885LAP3 4651/4885MEN1 1710/4885
US-20250333498-A1 ANTI-CLDN18.2 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF CNTN1, EPCAM, SLC22A8 ALDH1A1 728/4885LAP3 1437/4885MEN1 2360/4885
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VEGFA, VIP, AREG ALDH1A1 2585/4885LAP3 1496/4885MEN1 924/4885
US-20250381283-A1 METHOD FOR TREATING SOLID TUMOR TPM4, TPM3, TPST2 ALDH1A1 1289/4885LAP3 2203/4885MEN1 2103/4885
US-20220372152-A1 ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF IL23R, CD22, IL2RA ALDH1A1 1167/4885LAP3 51/4885MEN1 3404/4885
US-11332535-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IL23R, CD22, IL2RA ALDH1A1 1167/4885LAP3 51/4885MEN1 3404/4885
US-20250262316-A1 ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF FCGR2A, FCGR1A, FCGR3B ALDH1A1 378/4885LAP3 1290/4885MEN1 1874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.