Ostruthin

Ostruthin

SCHEMBL2936121

CC(C)=CCCC(C)=CCc1cc2ccc(=O)oc2cc1O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.74
CA9 Q16790 2/20 0.74
CA1 P00915 1/20 0.74
CA2 P00918 1/20 0.74
CA7 P43166 1/20 0.74
CA13 Q8N1Q1 1/20 0.74
SRD5A1 P18405 1/20 0.60
ALOX15 P16050 6/20 0.58
KDM4E B2RXH2 4/20 0.58
ALDH1A1 P00352 4/20 0.58
CYP3A4 P08684 4/20 0.58
HPGD P15428 4/20 0.58
TDP1 Q9NUW8 3/20 0.58
NDUFS8 O00217 2/20 0.58
COXFA4 O00483 2/20 0.58
NDUFAB1 O14561 2/20 0.58
NDUFA1 O15239 2/20 0.58
NDUFS4 O43181 2/20 0.58
NDUFB5 O43674 2/20 0.58
NDUFB3 O43676 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ostruthin SCHEMBL2936116 1.00 CA12 (0.74) CA12CA9CA1CA2CA7
Demethylsuberosin SCHEMBL4773171 0.89 CA9 (0.78) CA12CA9CA1CA2CA7
SCHEMBL4882410 0.79 CA9 (0.71) CA12CA9CA1CA2CA7
SCHEMBL4882406 0.79 CA9 (0.71) CA12CA9CA1CA2CA7
SCHEMBL9714250 0.77 PTPN1 (0.61) PPARGBACE1PTPN1ALOX5PTGS1
SCHEMBL9714237 0.77 PTPN1 (0.61) PPARGBACE1PTPN1ALOX5PTGS1
SCHEMBL24075636 0.76 MAOA (0.78) SRD5A1ALOX15KDM4EALDH1A1CYP3A4
SCHEMBL4540197 0.76 VKORC1 (0.60) CA12CA9ALOX15KDM4EALDH1A1
SCHEMBL30158338 0.76 MAOA (0.78) SRD5A1ALOX15KDM4EALDH1A1CYP3A4
SCHEMBL4540200 0.76 VKORC1 (0.60) CA12CA9ALOX15KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES NATURAL EXTRACTION SYS LLC (US) 2026-02-19 US disclosed
US-20250311723-A1 METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS IMPELLO BIOSCIENCES, INC. 2025-10-09 US disclosed
US-12409152-B2 Compositions and methods related to dissolved oxides Natural Extraction Systems, LLC (US) 2025-09-09 US disclosed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US disclosed
US-12065679-B2 Aspergillus oryzae and its application WENZHOU UNIVERSITY (CN) 2024-08-20 US disclosed
US-20240150269-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS MCMASTER UNIVERSITY (CA) 2024-05-09 US disclosed
US-20240041062-A1 FILLERS FOR CHOCOLATE AND OTHER CONSUMABLES Voyage Foods, Inc. 2024-02-08 US disclosed
EP-2229169-A1 PREPARATION CONTAINING CHROMANE-2-ONE DERIVATIVES Merck Patent GmbH (DE) 2010-09-22 EP disclosed
WO-2009089880-A1 PREPARATION CONTAINING CHROMANE-2-ONE DERIVATIVES MERCK PATENT GMBH (DE) 2009-07-23 WO disclosed
WO-2008100977-A2 CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS N.V. ORGANON (NL) 2008-08-21 WO disclosed
WO-2007115181-A9 COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF EASTMAN CHEM CO (US) 2008-04-03 WO disclosed
US-20070254859-A1 Compounds exhibiting efflux inhibitor activity and composition and uses thereof EASTMAN CHEMICAL COMPANY 2007-11-01 US disclosed
WO-2007115181-A2 COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF EASTMAN CHEMICAL COMPANY (US) 2007-10-11 WO disclosed
WO-2006094327-A1 PHARMACEUTICAL PREPARATION FOR TREATING MYCOBACTERIAL INFECTIONS Universität Graz (AT) 2006-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254859-A1 Compounds exhibiting efflux inhibitor activity and composition and uses thereof ABCC4, NCOA4, NR4A3 CA12 4180/4885CA9 2021/4885CA1 3736/4885
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB CA12 819/4885CA9 655/4885CA1 666/4885
US-20250311723-A1 METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS ERG28, AHCY, BROX CA12 2899/4885CA9 2263/4885CA1 3522/4885
US-12409152-B2 Compositions and methods related to dissolved oxides PRKG2, PRKG1, CIT CA12 262/4885CA9 159/4885CA1 61/4885
US-20240150269-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS ADH1A, ADH1C, AHR CA12 3047/4885CA9 1745/4885CA1 1621/4885
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES SCO2, CNR2, CNR1 CA12 315/4885CA9 1360/4885CA1 142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.