SCHEMBL29368148

SCHEMBL29368148

CNC(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)[C@H](CC(C)C)[C@H](C)C(=O)NO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MMP1 P03956 19/20 1.00
▸ MMP3 P08254 5/20 1.00
▸ MMP9 P14780 2/20 1.00
▸ ADAM17 P78536 1/20 1.00
▸ MMP2 P08253 4/20 0.76
▸ MMP7 P09237 1/20 0.69
▸ MMP8 P22894 1/20 0.69
▸ MMP13 P45452 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6850869 1.00 MMP1 (1.00) MMP1MMP3MMP9ADAM17MMP2
SCHEMBL10429973 0.90 MMP1 (0.82) MMP1MMP3MMP9ADAM17MMP2
SCHEMBL10429916 0.87 MMP1 (0.77) MMP1MMP3MMP9ADAM17MMP2
SCHEMBL10451735 0.86 MMP1 (1.00) MMP1MMP3MMP9ADAM17MMP2
SCHEMBL15505966 0.86 MMP1 (1.00) MMP1MMP3MMP9ADAM17MMP2
SCHEMBL10451722 0.84 MMP1 (0.83) MMP1MMP3MMP9ADAM17MMP2
SCHEMBL9650310 0.83 MMP1 (0.86) MMP1MMP3MMP9ADAM17
SCHEMBL7276467 0.82 MMP1 (1.00) MMP1MMP3MMP9ADAM17
SCHEMBL7284842 0.82 MMP1 (1.00) MMP1MMP3MMP9ADAM17MMP2
SCHEMBL7278285 0.82 MMP1 (1.00) MMP1MMP3MMP9ADAM17MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646198-A1 MK2 DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-11-12 — — EP claimed
CN-119685215-A Metazoan preparation for pets and preparation method and application thereof 内蒙古科拓微生态科技发展有限公司 2025-03-25 — — CN claimed
WO-2024148060-A1 MK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2024-07-11 — — WO claimed
US-20260125397-A1 MK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 — — US disclosed
US-20260102959-A1 METHODS FOR EXTRUDING ELASTOMERIC COMPOSITIONS CABOT CORP (US) 2026-04-16 — — US disclosed
US-20260103572-A1 METHODS FOR PREPARING ELASTOMER COMPOSITES WITH MIXER VENTILATION CABOT CORP (US) 2026-04-16 — — US disclosed
US-20260092160-A1 METHODS OF PREPARING A COMPOSITE HAVING ELASTOMER AND FILLER BEYOND LOTUS LLC (US) 2026-04-02 — — US disclosed
EP-4646198-A1 MK2 DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-11-12 — — EP disclosed
EP-4638436-A1 PRMT5 INHIBITORS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2025-10-29 — — EP disclosed
US-12351587-B2 Bicyclic compound as RIP-1 kinase inhibitor and application thereof MEDSHINE DISCOVERY INC. (CN) 2025-07-08 — — US disclosed
US-12344728-B2 Methods of preparing a composite having elastomer and filler BEYOND LOTUS LLC (US) 2025-07-01 — — US disclosed
WO-2022125679-A1 METHODS OF PREPARING A COMPOSITE HAVING ELASTOMER, FILLER, AND LINKING AGENTS BEYOND LOTUS LLC (US) 2022-06-16 — — WO disclosed
US-11319305-B2 Pyrimidine sulfamide derivative and preparation method and medical application thereof Shijiazhuang Sagacity New Drug Development Co., Ltd. (CN) 2022-05-03 — — US disclosed
CN-111937319-B Communication method, communication device and system 华为技术有限公司 2022-04-26 — — CN disclosed
EP-3978492-A1 BICYCLIC COMPOUND AS RIP-1 KINASE INHIBITOR AND APPLICATION THEREOF Medshine Discovery Inc. (CN) 2022-04-06 — — EP disclosed
CN-114206571-A Method for producing a composite comprising an elastomer and a filler 超越莲花有限责任公司 2022-03-18 — — CN disclosed
US-11277176-B2 Communication method, communications apparatus, and communications system HUAWEI TECHNOLOGIES CO., LTD. (CN) 2022-03-15 — — US disclosed
CN-114174399-A Tire tread 超越莲花有限责任公司 2022-03-11 — — CN disclosed
US-20220061324-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-03-03 — — US disclosed
CN-114008038-A Bicyclofused compound as RIP-1 kinase inhibitor and application thereof 南京明德新药研发有限公司 2022-02-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103572-A1 METHODS FOR PREPARING ELASTOMER COMPOSITES WITH MIXER VENTILATION EXOSC9, RPL30, EXOSC5 MMP1 1878/4885MMP3 2658/4885MMP9 2121/4885
US-12351587-B2 Bicyclic compound as RIP-1 kinase inhibitor and application thereof RIPK1, RIPK2, RIPK3 MMP1 2969/4885MMP3 3414/4885MMP9 2580/4885
US-11319305-B2 Pyrimidine sulfamide derivative and preparation method and medical application thereof TBXA2R, P2RY11, TPMT MMP1 4392/4885MMP3 4737/4885MMP9 4432/4885
US-20220061324-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS DDT, ACHE, AADAC MMP1 4125/4885MMP3 4144/4885MMP9 4562/4885
US-20260125397-A1 MK2 DEGRADERS AND USES THEREOF NR2C2, NR3C2, OXER1 MMP1 361/4885MMP3 1205/4885MMP9 1387/4885
US-20260092160-A1 METHODS OF PREPARING A COMPOSITE HAVING ELASTOMER AND FILLER COL2A1, COL14A1, COL1A1 MMP1 1175/4885MMP3 587/4885MMP9 1108/4885
US-20260102959-A1 METHODS FOR EXTRUDING ELASTOMERIC COMPOSITIONS SMCHD1, VCP, NSF MMP1 1157/4885MMP3 1680/4885MMP9 2236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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