SCHEMBL29369035

SCHEMBL29369035

CC(C)CC1NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(CCCNC(=N)N)NC(=O)C(NC(=O)C(N)CCC(=O)O)CSSCC2NC(=O)C3CSSCC(C(=O)NC(C(=O)NC(Cc4c[nH]c5ccccc45)C(=O)NC(CC(=O)O)C(=O)NCC(=O)NC(C(=O)NC(Cc4ccccc4)C(=O)NC(CO)C(=O)O)C(C)O)C(C)C)NC(=O)C(Cc4c[nH]c5ccccc45)NC(=O)CNC(=O)C(Cc4c[nH]cn4)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CSSCC(NC(=O)CNC(=O)CNC1=O)C(=O)NC(CO)C(=O)NC(C)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)N3)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]cn1)NC(=O)C(CCCCN)NC2=O

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 1/20 0.67
KCNMB4 Q86W47 1/20 0.67
RXFP1 Q9HBX9 1/20 0.65
RXFP4 Q8TDU9 5/20 0.60
RXFP3 Q9NSD7 5/20 0.60
F11 P03951 1/20 0.58
MC4R P32245 2/20 0.58
MC1R Q01726 2/20 0.58
KLK7 P49862 1/20 0.57
INSR P06213 1/20 0.54
TET2 Q6N021 1/20 0.54
TET1 Q8NFU7 1/20 0.54
TSLP Q969D9 2/20 0.54
PRLHR P49683 2/20 0.53
SSTR2 P30874 1/20 0.53
MC3R P41968 1/20 0.52
NR3C1 P04150 1/20 0.52
F12 P00748 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29993740 0.86 RXFP1 (0.55) KCNMA1KCNMB4RXFP1RXFP4RXFP3
SCHEMBL29356518 0.81 KCNMA1 (0.59) KCNMA1KCNMB4RXFP1RXFP4RXFP3
SCHEMBL29424808 0.80 RXFP1 (0.67) KCNMA1KCNMB4RXFP1RXFP4RXFP3
SCHEMBL29389059 0.80 KCNMA1 (0.66) KCNMA1KCNMB4RXFP1RXFP4RXFP3
SCHEMBL29438822 0.79 KCNMA1 (0.66) KCNMA1KCNMB4RXFP1RXFP4RXFP3
SCHEMBL29438955 0.77 MC4R (0.66) KCNMA1KCNMB4RXFP1RXFP4RXFP3
SCHEMBL22861993 0.77 TET2 (0.57) F11TET2TET1TSLPSSTR2
SCHEMBL24919541 0.77 TET2 (0.56) F11TET2TET1TSLPF12
SCHEMBL22861964 0.77 TET2 (0.56) F11TET2TET1TSLPF12
SCHEMBL31211808 0.76 TSLP (0.50) KCNMA1KCNMB4TET2TET1TSLP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119185569-A Sustained release delivery system comprising a traceless linker 诺华股份有限公司 2024-12-27 CN claimed
US-20240002547-A1 THERAPEUTIC MULTI-TARGETING CONSTRUCTS AND USES THEREOF AEBI LTD (IL) 2024-01-04 US claimed
US-11236360-B2 Adeno-associated viruses engineered for selectable tropism REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2022-02-01 US claimed
US-12606937-B2 Humanized antibodies with ultralong complementary determining regions TAURUS BIOSCIENCES, LLC (US) 2026-04-21 US disclosed
US-20260001922-A1 PEPTIDES TARGETING SODIUM CHANNELS TO TREAT PAIN UNIV CALIFORNIA (US) 2026-01-01 US disclosed
US-12433949-B2 Sustained release delivery systems comprising traceless linkers NOVARTIS AG (CH) 2025-10-07 US disclosed
WO-2025137555-A1 POLYPEPTIDES THAT BIND TO NKP46 OMNIAB, INC. (US) 2025-06-26 WO disclosed
CN-119185569-A Sustained release delivery system comprising a traceless linker 诺华股份有限公司 2024-12-27 CN disclosed
US-20240012004-A1 INCREASED VOLTAGE-GATED SODIUM CHANNEL ALPHA PROTEIN SUBUNIT EXPRESSION THROUGH VIRAL 2A-MEDIATED CO-EXPRESSION OF NAV BETA SUBUNITS MERCK SHARP & DOHME LLC (US) 2024-01-11 US disclosed
US-20240002547-A1 THERAPEUTIC MULTI-TARGETING CONSTRUCTS AND USES THEREOF AEBI LTD (IL) 2024-01-04 US disclosed
US-20230287598-A1 HUMANIZED ANTIBODIES WITH ULTRALONG COMPLEMENTARY DETERMINING REGIONS TAURUS BIOSCIENCES, LLC 2023-09-14 US disclosed
US-11739163-B2 Therapeutic multi-targeting constructs and uses thereof AEBI LTD. (IL) 2023-08-29 US disclosed
US-20230201353-A1 SUSTAINED RELEASE DELIVERY SYSTEMS COMPRISING TRACELESS LINKERS NOVARTIS AG (CH) 2023-06-29 US disclosed
US-11530493-B2 Humanized antibodies with ultralong complementary determining regions TAURUS BIOSCIENCES, LLC (US) 2022-12-20 US disclosed
WO-2022108832-A1 INCREASED VOLTAGE-GATED SODIUM CHANNEL ALPHA PROTEIN SUBUNIT EXPRESSION THROUGH VIRAL 2A-MEDIATED CO-EXPRESSION OF NAV BETA SUBUNITS MERCK SHARP & DOHME CORP. (US) 2022-05-27 WO disclosed
US-11236360-B2 Adeno-associated viruses engineered for selectable tropism REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2022-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606937-B2 Humanized antibodies with ultralong complementary determining regions IGLV6-57, FCGR3B, VSIR KCNMA1 2682/4885KCNMB4 742/4885RXFP1 1234/4885
US-20230201353-A1 SUSTAINED RELEASE DELIVERY SYSTEMS COMPRISING TRACELESS LINKERS ABCB11, ABCB1, GHRHR KCNMA1 4420/4885KCNMB4 3598/4885RXFP1 714/4885
US-11739163-B2 Therapeutic multi-targeting constructs and uses thereof CD47, GZMB, CD44 KCNMA1 3460/4885KCNMB4 2969/4885RXFP1 2964/4885
US-20260001922-A1 PEPTIDES TARGETING SODIUM CHANNELS TO TREAT PAIN TPX2, XBP1, SCN9A KCNMA1 379/4885KCNMB4 233/4885RXFP1 129/4885
US-12433949-B2 Sustained release delivery systems comprising traceless linkers ABCB11, ABCB1, GHRHR KCNMA1 4420/4885KCNMB4 3598/4885RXFP1 714/4885
US-20240002547-A1 THERAPEUTIC MULTI-TARGETING CONSTRUCTS AND USES THEREOF CD47, GZMB, CD44 KCNMA1 3460/4885KCNMB4 2969/4885RXFP1 2964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.