Demiditraz

Demiditraz

SCHEMBL29388955

Cc1cccc([C@H](C)c2ncc[nH]2)c1C

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 6/20 0.61
ADRA2B P18089 6/20 0.61
ADRA2C P18825 6/20 0.61
ADRA1A P35348 3/20 0.50
ADRA1B P35368 3/20 0.50
ADRA1D P25100 2/20 0.50
KCNH2 Q12809 1/20 0.50
TP53 P04637 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C19 P33261 1/20 0.50
SLC6A2 P23975 1/20 0.49
HTR7 P34969 1/20 0.49
F2RL1 P55085 7/20 0.46
TAAR1 Q96RJ0 2/20 0.43
NISCH Q9Y2I1 2/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demiditraz SCHEMBL696353 1.00 ADRA2A (0.61) ADRA2AADRA2BADRA2CADRA1AADRA1B
Demiditraz SCHEMBL697081 1.00 ADRA2A (0.61) ADRA2AADRA2BADRA2CADRA1AADRA1B
Demiditraz SCHEMBL617479 1.00 ADRA2A (0.61) ADRA2AADRA2BADRA2CADRA1AADRA1B
Demiditraz SCHEMBL28114617 0.93 ADRA2A (0.55) ADRA2AADRA2BADRA2CADRA1AADRA1B
SCHEMBL3532392 0.86 ADRA2A (0.57) ADRA2AADRA2BADRA2CADRA1AADRA1B
SCHEMBL702593 0.86 ADRA2A (0.57) ADRA2AADRA2BADRA2CADRA1AADRA1B
SCHEMBL13034019 0.86 ADRA2A (0.57) ADRA2AADRA2BADRA2CADRA1AADRA1B
SCHEMBL700615 0.86 ADRA2A (0.57) ADRA2AADRA2BADRA2CADRA1AADRA1B
SCHEMBL14462564 0.86 ADRA2A (0.57) ADRA2AADRA2BADRA2CADRA1AADRA1B
SCHEMBL702854 0.84 ADRA2A (0.58) ADRA2AADRA2BADRA2CADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230381173-A1 METHODS AND PHARMACEUTICAL COMPOSITION FOR TREATING DISEASES TONGLI BIOMEDICAL CO., LTD. (CN) 2023-11-30 US claimed
US-20220323472-A1 ANTI-PARASITIC COMPOUNDS FOR THE TREATMENT AND PREVENTION OF VIRAL DISEASES SPALLITTA FRANK ANTHONY (US) 2022-10-13 US claimed
WO-2022212399-A1 ANTI-PARASITIC COMPOUNDS FOR THE TREATMENT AND PREVENTION OF VIRAL DISEASES SPALLITTA FRANK ANTHONY (US) 2022-10-06 WO claimed
WO-2022171150-A1 METHODS AND PHARMACEUTICAL COMPOSITION FOR TREATING DISEASES TONGLI BIOMEDICAL CO., LTD. (CN) 2022-08-18 WO claimed
US-20220046921-A1 MESOSTIGMATA MITE CONTROL COMPOSITION MEIJI SEIKA PHARMA CO., LTD. (JP) 2022-02-17 US claimed
CN-116969925-B Heteroaryl-triazole compounds BAYER AG (DE) 2026-05-26 CN disclosed
EP-4737442-A1 DIAMINOVINYLIDENE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAID COMPOUND, AND METHODS FOR USING THESE ADEKA CORPORATION (JP) 2026-05-06 EP disclosed
US-12610949-B2 Heteroaryl-triazole compounds as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2026-04-28 US disclosed
US-12612386-B2 Heteroaryl-triazole compounds as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2026-04-28 US disclosed
US-20260108498-A1 METHOD OF ERADICATING TICKS THAT ATTACH TO HUMANS USING LOTILANER FORMULATIONS TARSUS PHARMACEUTICALS INC (US) 2026-04-23 US disclosed
EP-4041393-B1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AG (DE) 2026-04-08 EP disclosed
US-12593845-B2 2,6-dioxo-3,6-dihydropyrimidine compound, agricultural and horticultural bactericide, nematicide, and medical and veterinary antifungal agent NIPPON SODA CO., LTD. (JP) 2026-04-07 US disclosed
WO-2022053453-A1 AZOLE CARBOXAMIDE AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2022-03-17 WO disclosed
EP-3514146-B1 DIARYL- AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO (JP) 2022-03-16 EP disclosed
CN-109689662-B Fused bicyclic heterocyclic derivatives as pest control agents 拜耳作物科学股份公司 2022-03-15 CN disclosed
WO-2022049149-A1 CHEWABLE FORMULATIONS ELANCO TIERGESUNDHEIT AG (CH) 2022-03-10 WO disclosed
US-20220061325-A1 PYRIDINE N-OXIDE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2022-03-03 US disclosed
US-20220054457-A2 METHODS FOR TREATING OCULAR DEMODEX USING SPINOSAD FORMULATIONS TARSUS PHARMACEUTICALS, INC. 2022-02-24 US disclosed
US-11254661-B2 Quinoline derivatives for treating infections with helminths BAYER ANIMAL HEALTH GMBH 2022-02-22 US disclosed
US-20220046921-A1 MESOSTIGMATA MITE CONTROL COMPOSITION MEIJI SEIKA PHARMA CO., LTD. (JP) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12610949-B2 Heteroaryl-triazole compounds as pesticides CTRL, PTMS, DDT ADRA2A 2387/4885ADRA2B 2446/4885ADRA2C 786/4885
US-12593845-B2 2,6-dioxo-3,6-dihydropyrimidine compound, agricultural and horticultural bactericide, nematicide, and medical and veterinary antifungal agent CASP6, GMDS, HPD ADRA2A 4575/4885ADRA2B 4528/4885ADRA2C 4057/4885
US-12612386-B2 Heteroaryl-triazole compounds as pesticides CBR3, CYCS, HCN1 ADRA2A 3108/4885ADRA2B 3060/4885ADRA2C 408/4885
US-20220061325-A1 PYRIDINE N-OXIDE COMPOUND AND PEST CONTROL AGENT NOXO1, NOX1, NOX3 ADRA2A 1188/4885ADRA2B 1206/4885ADRA2C 1343/4885
US-20220323472-A1 ANTI-PARASITIC COMPOUNDS FOR THE TREATMENT AND PREVENTION OF VIRAL DISEASES CTSA, DDT, CTSV ADRA2A 3614/4885ADRA2B 3474/4885ADRA2C 3392/4885
US-20260108498-A1 METHOD OF ERADICATING TICKS THAT ATTACH TO HUMANS USING LOTILANER FORMULATIONS ITGB7, ITGA1, ILK ADRA2A 1740/4885ADRA2B 1903/4885ADRA2C 1738/4885
US-11254661-B2 Quinoline derivatives for treating infections with helminths RECQL, HRH2, HRH4 ADRA2A 812/4885ADRA2B 995/4885ADRA2C 545/4885
US-20220046921-A1 MESOSTIGMATA MITE CONTROL COMPOSITION DNMT1, TYR, DDT ADRA2A 1492/4885ADRA2B 2324/4885ADRA2C 961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.