SCHEMBL29398150

SCHEMBL29398150

CCCC[C@H](NC(C)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.70

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 2/20 0.65
▸ IL23R Q5VWK5 6/20 0.62
▸ CCKBR P32239 2/20 0.59
▸ GHSR Q92847 2/20 0.59
▸ MC4R P32245 2/20 0.58
▸ NPBWR1 P48145 2/20 0.58
▸ CXCR4 P61073 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29357687 0.86 KISS1R (0.62) KISS1RMC4R
SCHEMBL26006274 0.85 KISS1R (0.64) KISS1RGHSRMC4R
SCHEMBL29359331 0.85 KISS1R (0.64) KISS1RGHSRMC4R
SCHEMBL26006253 0.85 KISS1R (0.64) KISS1RGHSRMC4R
SCHEMBL21146569 0.82 IL23R (0.66) IL23RMC4R
SCHEMBL29527343 0.82 NPY1R (0.70) KISS1RCCKBRGHSRMC4RNPBWR1
SCHEMBL25767621 0.81 MC4R (0.66) KISS1RGHSRMC4RNPBWR1CXCR4
SCHEMBL29500559 0.80 CCKBR (0.67) KISS1RCCKBRGHSRNPBWR1
SCHEMBL30999649 0.80 KISS1R (0.57) KISS1RIL23RCCKBRNPBWR1
SCHEMBL29546807 0.79 GHSR (0.90) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117083060-A Topical patches for targeted siRNA nanocomposite delivery and gene therapy: composition, method for producing same, and use thereof 南洋理工大学 2023-11-17 — — CN claimed
WO-2022159036-A1 TOPICAL PATCH FOR TARGETED siRNA NANOPLEX DELIVERY AND GENE THERAPIES: COMPOSITION, METHOD OF MAKING AND USE THEREOF NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-07-28 — — WO claimed
EP-3432934-B1 PRODRUGS OF CYTOTOXIC AGENTS WITH ENZYMATICALLY CLEAVABLE GROUPS Bayer Pharma AG (DE) 2022-02-23 — — EP claimed
US-20250332298-A1 PEPTIDE-COUPLED ALGINATE GELS COMPRISING RADIONUCLIDES BLUE WAVE THERAPEUTICS GMBH (CH) 2025-10-30 — — US disclosed
US-20250275931-A1 TOPICAL PATCH COMPOSITION FOR TARGETED SIRNA NANOPLEX DELIVERY AND GENE THERAPIES AND METHOD OF MAKING AND USE THEREOF National Skin Centre (Singapore) Pte Ltd (SG) 2025-09-04 — — US disclosed
US-20240408247-A1 NON-PEPTIDE TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-12-12 — — US disclosed
US-20240285628-A1 NON-PEPTIDE TARGETED THERAPEUTICS AND USES THEREOF Crinetics Pharmaceuticals, Inc. 2024-08-29 — — US disclosed
US-12059472-B2 Prodrugs of cytotoxic active agents having enzymatically cleavable groups BAYER AKTIENGESELLSCHAFT (DE) 2024-08-13 — — US disclosed
EP-4351654-A1 NON-PEPTIDE TARGETED THERAPEUTICS AND USES THEREOF Crinetics Pharmaceuticals, Inc. (US) 2024-04-17 — — EP disclosed
EP-4351653-A1 NON-PEPTIDE TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2024-04-17 — — EP disclosed
US-20240043379-A1 PRODRUGS OF CYTOTOXIC ACTIVE AGENTS HAVING ENZYMATICALLY CLEAVABLE GROUPS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2024-02-08 — — US disclosed
CN-114794099-A Nitrogen-containing surfactants for use in agriculture 诺力昂化学品国际有限公司 2022-07-29 — — CN disclosed
WO-2022159036-A1 TOPICAL PATCH FOR TARGETED siRNA NANOPLEX DELIVERY AND GENE THERAPIES: COMPOSITION, METHOD OF MAKING AND USE THEREOF NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-07-28 — — WO disclosed
CN-109068645-B Mixtures and compositions comprising a paenibacillus strain or fusaricidin and a chemical pesticide 巴斯夫欧洲公司 2022-07-08 — — CN disclosed
CN-114599644-A Nicotinamide compound and herbicide composition containing the same 韩国化学研究院 2022-06-07 — — CN disclosed
CN-111801014-B Fungicidal compositions of cloroxen 巴斯夫农业公司 2022-05-27 — — CN disclosed
CN-111771885-B Pest control composition comprising novel iminopyridine derivatives 株式会社MMAG 2022-05-17 — — CN disclosed
CN-108366563-B Herbicide mixture and preparation for potatoes 阿达玛阿甘有限公司 2022-03-25 — — CN disclosed
CN-110868861-B Agricultural compositions 萨卡帕·瓦达卡库塔 2022-03-15 — — CN disclosed
EP-3432934-B1 PRODRUGS OF CYTOTOXIC AGENTS WITH ENZYMATICALLY CLEAVABLE GROUPS Bayer Pharma AG (DE) 2022-02-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12059472-B2 Prodrugs of cytotoxic active agents having enzymatically cleavable groups LGMN, BUB1B, KIF15 KISS1R 2772/4885IL23R 4431/4885CCKBR 4555/4885
US-20240408247-A1 NON-PEPTIDE TARGETED THERAPEUTICS AND USES THEREOF GRPR, SCTR, NPSR1 KISS1R 1398/4885IL23R 505/4885CCKBR 244/4885
US-20240285628-A1 NON-PEPTIDE TARGETED THERAPEUTICS AND USES THEREOF GRPR, SCTR, NPSR1 KISS1R 1398/4885IL23R 505/4885CCKBR 244/4885
US-20250332298-A1 PEPTIDE-COUPLED ALGINATE GELS COMPRISING RADIONUCLIDES ALG1, ALG3, GRPR KISS1R 205/4885IL23R 891/4885CCKBR 178/4885
US-20240043379-A1 PRODRUGS OF CYTOTOXIC ACTIVE AGENTS HAVING ENZYMATICALLY CLEAVABLE GROUPS BUB1B, KIF5B, TK1 KISS1R 3755/4885IL23R 4668/4885CCKBR 4780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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