SCHEMBL29416601

SCHEMBL29416601

NC(=O)Nc1ccc(C(F)(F)F)cc1F

nearest known ligand 0.77

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 9/20 0.77
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
TRPV1 Q8NER1 1/20 0.47
PTGS1 P23219 2/20 0.46
NTRK1 P04629 1/20 0.46
TSHR P16473 1/20 0.46
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14959294 1.00 KIF11 (0.77) KIF11MEN1KMT2ATRPV1PTGS1
SCHEMBL5422208 0.87 KIF11 (1.00) KIF11PTGS1
SCHEMBL60290 0.86 KIF11 (0.63) KIF11MEN1KMT2ATRPV1PTGS1
SCHEMBL29572624 0.86 KIF11 (0.63) KIF11MEN1KMT2ATRPV1PTGS1
SCHEMBL11095537 0.86 KIF11 (0.59) KIF11MEN1KMT2ATRPV1NTRK1
SCHEMBL19358889 0.84 KIF11 (0.56) KIF11MEN1KMT2ATRPV1NTRK1
SCHEMBL11883526 0.83 KIF11 (0.55) KIF11MEN1KMT2ATRPV1NTRK1
SCHEMBL9185909 0.83 CYP1A2 (0.56) KIF11MEN1KMT2ATSHR
SCHEMBL31434967 0.83 CYP1A2 (0.56) KIF11MEN1KMT2ATSHR
SCHEMBL4796235 0.83 KIF11 (0.59) KIF11MEN1KMT2APTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574131-A Heterocyclic compounds for insect repellent 勃林格殷格翰动物保健有限公司 2026-02-27 CN disclosed
US-12559503-B2 Anthelmintic aza-benzothiophene and aza-benzofuran compounds BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2026-02-24 US disclosed
WO-2025202940-A2 ANTIPARASITIC CYCLIC DEPSIPEPTIDES ANIMOL DISCOVERY, INC. (US) 2025-10-02 WO disclosed
EP-3525590-B1 PESTICIDAL AND PARASITICIDAL VINYL ISOXAZOLINE COMPOUNDS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-08-20 EP disclosed
US-20250243197-A1 Anthelmintic Heterocyclic Compounds BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-07-31 US disclosed
WO-2025149943-A1 ANTIPARASITIC CYCLIC DEPSIPEPTIDES ANIMOL DISCOVERY, INC. (US) 2025-07-17 WO disclosed
WO-2025120611-A1 ANTIPARASITIC COMPOUNDS ANIMOL DISCOVERY, INC. (US) 2025-06-12 WO disclosed
US-12312356-B2 Anthelmintic heterocyclic compounds BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-05-27 US disclosed
US-12286455-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2025-04-29 US disclosed
US-12269822-B2 Anthelminthic heterocyclic compounds BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-04-08 US disclosed
US-11464763-B2 Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof Boehringer Ingelheim Animal Health USA Inc. (US) 2022-10-11 US disclosed
CN-114891070-A Anthelmintic depsipeptide compounds 勃林格殷格翰动物保健美国公司 2022-08-12 CN disclosed
US-11382949-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2022-07-12 US disclosed
WO-2022140728-A1 PARASITICIDAL COLLAR COMPRISING ISOXAZOLINE COMPOUNDS BOEHRINGER INGELHEIM ANIMAM HEALTH USA INC. (US) 2022-06-30 WO disclosed
US-20220202835-A1 INJECTABLE CLORSULON COMPOSITIONS, METHODS AND USES THEREOF Boehringer Ingelheim Animal Health USA Inc. (US) 2022-06-30 US disclosed
CN-114573573-A Antiparasitic isoxazoline compounds, long-acting injectable formulations containing them, methods and uses thereof 勃林格殷格翰动物保健美国公司 2022-06-03 CN disclosed
CN-107835818-B Anthelmintic depsipeptide compounds 勃林格殷格翰动物保健美国公司 2022-04-29 CN disclosed
US-20220098241-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS Boehringer Ingelheim Animal Health USA Inc. (US) 2022-03-31 US disclosed
CN-109068651-B Antiparasitic isoxazoline compounds, long-acting injectable formulations containing them, methods and uses thereof 勃林格殷格翰动物保健美国公司 2022-03-01 CN disclosed
US-20220048903-A1 Anthelminthic Heterocyclic Compounds BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11382949-B2 Anthelmintic depsipeptide compounds ENPP2, ROCK2, RRP12 KIF11 3657/4885MEN1 2930/4885KMT2A 1158/4885
US-20220202835-A1 INJECTABLE CLORSULON COMPOSITIONS, METHODS AND USES THEREOF IL5, IL17A, IL33 KIF11 1943/4885MEN1 1718/4885KMT2A 4386/4885
US-11464763-B2 Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof EPX, P2RX7, CYP4X1 KIF11 2863/4885MEN1 4411/4885KMT2A 2270/4885
US-12312356-B2 Anthelmintic heterocyclic compounds AADAC, HNMT, HRH4 KIF11 3317/4885MEN1 1548/4885KMT2A 642/4885
US-20220048903-A1 Anthelminthic Heterocyclic Compounds SDHA, PAH, PIGS KIF11 2068/4885MEN1 2676/4885KMT2A 1440/4885
US-20220098241-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS VIP, PREP, DNPEP KIF11 2884/4885MEN1 1735/4885KMT2A 2523/4885
US-12269822-B2 Anthelminthic heterocyclic compounds SDHA, PAH, PIGS KIF11 2068/4885MEN1 2676/4885KMT2A 1440/4885
US-20250243197-A1 Anthelmintic Heterocyclic Compounds PAH, PIGS, SDHA KIF11 2212/4885MEN1 1888/4885KMT2A 1729/4885
US-12559503-B2 Anthelmintic aza-benzothiophene and aza-benzofuran compounds HDAC5, NR5A2, HRH4 KIF11 2701/4885MEN1 3843/4885KMT2A 820/4885
US-12286455-B2 Anthelmintic depsipeptide compounds VIP, PREP, DNPEP KIF11 3126/4885MEN1 1902/4885KMT2A 2407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.