SCHEMBL29445599

SCHEMBL29445599

CC(=O)NCSC[C@@H](C=O)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.51
KMT2A Q03164 2/20 0.43
EPHX2 P34913 1/20 0.41
MDM4 O15151 1/20 0.40
TP53 P04637 1/20 0.40
SLC17A5 Q9NRA2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25320019 0.84 SLC17A5 (0.54) CASP3KMT2AMDM4TP53SLC17A5
SCHEMBL29374576 0.84 SLC17A5 (0.54) CASP3KMT2AMDM4TP53SLC17A5
SCHEMBL29398952 0.84 CASP3 (0.45) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL29400856 0.84 SLC17A5 (0.54) CASP3KMT2AMDM4TP53SLC17A5
SCHEMBL120505 0.84 SLC17A5 (0.54) CASP3KMT2AMDM4TP53SLC17A5
SCHEMBL13570148 0.82 CASP3 (0.60) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL10187000 0.82 CASP3 (0.60) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL13573587 0.81 CASP3 (0.60) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL12510996 0.81 CASP3 (0.53) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL29445618 0.81 CASP3 (0.53) CASP3KMT2AEPHX2MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260096988-A1 DRUG DELIVERY METHODS AND COMPOSITIONS MAYO FOUND MEDICAL EDUCATION & RES (US) 2026-04-09 US disclosed
US-12496275-B2 Drug delivery methods and compositions MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2025-12-16 US disclosed
US-12492225-B2 Melanocyte-regulating peptides IDP DISCOVERY PHARMA, S.L. (ES) 2025-12-09 US disclosed
EP-4532513-A1 CYCLIC PEPTIDES WITH ANTIBACTERIAL ACTIVITY AGAINST MULTIDRUG RESISTANT (MDR) PATHOGENS Fundación Privada Instituto De Salud Global Barcelona (ES) 2025-04-09 EP disclosed
CN-119451974-A Cyclic peptides having antibacterial activity against Multiple Drug Resistant (MDR) pathogens 巴塞罗那全球健康研究所私人基金会 2025-02-14 CN disclosed
US-20240294573-A1 CONSTRAINED PEPTIDES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-09-05 US disclosed
US-12054560-B2 Bifunctional molecules recruiting antibodies and targeting cancer cells JIANGNAN UNIVERSITY (CN) 2024-08-06 US disclosed
US-20240083943-A1 VEGF-REGULATING PEPTIDES IDP DISCOVERY PHARMA, S.L. (ES) 2024-03-14 US disclosed
WO-2023227771-A1 CYCLIC PEPTIDES WITH ANTIBACTERIAL ACTIVITY AGAINST MULTIDRUG RESISTANT (MDR) PATHOGENS Fundación Privada Instituto De Salud Global Barcelona (ES) 2023-11-30 WO disclosed
EP-4271480-A1 VEGF-REGULATING PEPTIDES IDP Discovery Pharma, S.L. (ES) 2023-11-08 EP disclosed
EP-4039698-A1 PEPTIDES WITH ANTI-CANCER ACTIVITY IDP Discovery Pharma, S.L. (ES) 2022-08-10 EP disclosed
WO-2022144401-A1 VEGF-REGULATING PEPTIDES IDP DISCOVERY PHARMA, S.L. (ES) 2022-07-07 WO disclosed
EP-4023295-A1 VEGF-REGULATING PEPTIDES IDP Discovery Pharma, S.L. (ES) 2022-07-06 EP disclosed
EP-4007563-A1 MELANOCYTE-REGULATING PEPTIDES IDP Discovery Pharma, S.L. (ES) 2022-06-08 EP disclosed
US-11352395-B2 Anticancer peptides IDP DISCOVERY PHARMA, S.L. (ES) 2022-06-07 US disclosed
EP-3986914-A1 CONSTRAINED PEPTIDES TearSolutions, Inc. (US) 2022-04-27 EP disclosed
EP-3982942-A1 DRUG DELIVERY METHODS AND COMPOSITIONS Mayo Foundation for Medical Education and Research (US) 2022-04-20 EP disclosed
CN-114245800-A Melanocyte regulatory peptides IDP研发制药有限公司 2022-03-25 CN disclosed
US-11279734-B2 Solution-phase affinity selection of inhibitors from combinatorial peptide libraries MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-03-22 US disclosed
CN-114206916-A Restricted peptides 缇尔索卢森公司 2022-03-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492225-B2 Melanocyte-regulating peptides MC1R, MITF, MCHR1 CASP3 4704/4885KMT2A 995/4885EPHX2 3556/4885
US-12054560-B2 Bifunctional molecules recruiting antibodies and targeting cancer cells CD47, FCGR3B, FCGR2A CASP3 3653/4885KMT2A 2273/4885EPHX2 2065/4885
US-11279734-B2 Solution-phase affinity selection of inhibitors from combinatorial peptide libraries TP53, MDM2, MDM4 CASP3 2615/4885KMT2A 3182/4885EPHX2 3865/4885
US-20240294573-A1 CONSTRAINED PEPTIDES IAPP, NGLY1, VIP CASP3 1870/4885KMT2A 4628/4885EPHX2 4431/4885
US-20260096988-A1 DRUG DELIVERY METHODS AND COMPOSITIONS PCTP, LPXN, LITAF CASP3 490/4885KMT2A 4472/4885EPHX2 3182/4885
US-11352395-B2 Anticancer peptides PNISR, NGLY1, SLC1A5 CASP3 2512/4885KMT2A 1904/4885EPHX2 4215/4885
US-20240083943-A1 VEGF-REGULATING PEPTIDES VEGFA, FLT4, FLT1 CASP3 3795/4885KMT2A 3448/4885EPHX2 4156/4885
US-12496275-B2 Drug delivery methods and compositions LPXN, HDGF, LDLR CASP3 526/4885KMT2A 4745/4885EPHX2 2041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.