SCHEMBL29458102

SCHEMBL29458102

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)CN)C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C=O)CC(C)C

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 9/20 0.62
▸ NPY2R P49146 8/20 0.62
▸ NPY5R Q15761 8/20 0.62
▸ NPY1R P25929 6/20 0.62
▸ TFPI P10646 6/20 0.59
▸ AGTR1 P30556 3/20 0.55
▸ RAMP3 O60896 2/20 0.55
▸ CALCR P30988 2/20 0.55
▸ AGTR2 P50052 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Apidaecin SCHEMBL29380656 0.94 NPY4R (0.67) NPY4RNPY2RNPY5RNPY1RTFPI
Apidaecin Ia SCHEMBL29458103 0.93 NPY2R (0.63) NPY4RNPY2RNPY5RNPY1RTFPI
SCHEMBL29874441 0.87 NPY2R (0.69) NPY4RNPY2RNPY5RNPY1RTFPI
Apidaecin Ia SCHEMBL31694517 0.85 F2 (0.58) NPY4RNPY2RNPY5RNPY1RRAMP3
SCHEMBL29702101 0.83 F2 (0.58) NPY4RNPY2RNPY5RNPY1RTFPI
SCHEMBL29702111 0.83 F2 (0.61) NPY4RNPY2RNPY5RNPY1R
SCHEMBL18872896 0.82 AGTR1 (0.68) NPY4RNPY2RNPY5RNPY1RAGTR1
Drosocin SCHEMBL29539177 0.81 NPY2R (0.66) NPY4RNPY2RNPY5RNPY1RTFPI
SCHEMBL29358935 0.80 TFPI (0.64) NPY4RNPY2RNPY5RNPY1RTFPI
SCHEMBL18872894 0.80 AGTR1 (0.68) NPY4RNPY2RNPY5RNPY1RAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124274-A1 METHODS OF INCREASING READTHROUGH OF A PREMATURE TERMINATION CODON UNIV RAMOT (IL) 2026-05-07 — — US disclosed
US-20250368679-A1 FORMATION OF AMIDINES VANVELLER BRETT (US) 2025-12-04 — — US disclosed
WO-2025227105-A1 CLEAVABLE LINKERS WITH TUNABLE HALF-LIVES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-10-30 — — WO disclosed
US-20250281456-A1 METHODS OF TREATING CANCER BY INHIBITING BACTERIAL DNAK TO RESTORE ACTIVITIES OF ANTICANCER DRUGS UNIVERSITY OF MARYLAND, BALTIMORE 2025-09-11 — — US disclosed
CN-120574875-A Method for constructing high-expression genetic engineering bacteria of antibacterial peptide APIDAECIN IB 国家粮食和物资储备局科学研究院 2025-09-02 — — CN disclosed
CN-120574875-A Method for constructing high-expression genetic engineering bacteria of antibacterial peptide APIDAECIN IB 国家粮食和物资储备局科学研究院 2025-09-02 — — CN disclosed
US-12391733-B2 Stapled intracellular-targeting antimicrobial peptides to treat infection DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-08-19 — — US disclosed
US-20250256007-A1 GELMA POLYMER COMPOSITIONS COMPRISING CELLS GELMEDIX INC (US) 2025-08-14 — — US disclosed
WO-2025085609-A1 ACRYLATED GELATIN POLYMER COMPOSITIONS COMPRISING CELLS GELMEDIX, INC. (US) 2025-04-24 — — WO disclosed
EP-4511075-A1 GELMA POLYMER COMPOSITIONS COMPRISING CELLS Gelmedix, Inc. (US) 2025-02-26 — — EP disclosed
WO-2023196891-A2 METHODS OF TREATING CANCER BY INHIBITING BACTERIAL DNAK TO RESTORE ACTIVITIES OF ANTICANCER DRUGS UNIVERSITY OF MARYLAND, BALTIMORE (US) 2023-10-12 — — WO disclosed
WO-2023044389-A1 GELMA POLYMER COMPOSITIONS COMPRISING CORTICOSTEROIDS GELMEDIX, INC. (US) 2023-03-23 — — WO disclosed
WO-2023044385-A1 GELMA POLYMER COMPOSITIONS AND USES THEREOF GELMEDIX, INC. (US) 2023-03-23 — — WO disclosed
US-20220401561-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF AJ SCIENCES (YIXING) CO., LTD (CN) 2022-12-22 — — US disclosed
US-20220362381-A1 REMOTELY TRIGGERED THERAPY BAMBU VAULT LLC (US) 2022-11-17 — — US disclosed
WO-2022212362-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) 2022-10-06 — — WO disclosed
US-20220288273-A1 OSTEOINDUCTIVE MODIFIED GELATIN HYDROGELS AND METHODS OF MAKING AND USING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-09-15 — — US disclosed
EP-3328877-B1 PEPTOID THE UNIV OF DURHAM (GB) 2022-08-24 — — EP disclosed
EP-4037715-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF Beijing Xuanyi Pharmasciences Co., Ltd. (CN) 2022-08-10 — — EP disclosed
WO-2022076505-A1 GELMA POLYMER COMPOSITIONS AND USES THEREOF GELMEDIX, INC. (US) 2022-04-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124274-A1 METHODS OF INCREASING READTHROUGH OF A PREMATURE TERMINATION CODON RNMT, TRMT1L, UPF1 NPY4R 2419/4885NPY2R 3305/4885NPY5R 3256/4885
US-20250281456-A1 METHODS OF TREATING CANCER BY INHIBITING BACTERIAL DNAK TO RESTORE ACTIVITIES OF ANTICANCER DRUGS DCK, DTYMK, POLK NPY4R 4875/4885NPY2R 4862/4885NPY5R 4835/4885
US-20220362381-A1 REMOTELY TRIGGERED THERAPY CD47, HSP90AA1, HSF1 NPY4R 1871/4885NPY2R 2862/4885NPY5R 3059/4885
US-20250368679-A1 FORMATION OF AMIDINES H1-4, H1-2, H1-3 NPY4R 272/4885NPY2R 351/4885NPY5R 496/4885
US-20220401561-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF CD44, SSB, DNPEP NPY4R 4239/4885NPY2R 4224/4885NPY5R 4145/4885
US-12391733-B2 Stapled intracellular-targeting antimicrobial peptides to treat infection VIP, SPPL2B, HM13 NPY4R 3057/4885NPY2R 3252/4885NPY5R 3263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback