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Apidaecin

Apidaecin

SCHEMBL29380656

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)CN)C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 9/20 0.67
▸ NPY2R P49146 8/20 0.67
▸ NPY5R Q15761 8/20 0.67
▸ NPY1R P25929 6/20 0.67
▸ TFPI P10646 6/20 0.63
▸ RAMP3 O60896 3/20 0.60
▸ CALCR P30988 3/20 0.60
▸ AGTR1 P30556 2/20 0.59
▸ AGTR2 P50052 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Apidaecin Ia SCHEMBL29458103 0.96 NPY2R (0.63) NPY4RNPY2RNPY5RNPY1RTFPI
SCHEMBL29458102 0.94 NPY4R (0.62) NPY4RNPY2RNPY5RNPY1RTFPI
SCHEMBL29874441 0.90 NPY2R (0.69) NPY4RNPY2RNPY5RNPY1RTFPI
Apidaecin Ia SCHEMBL31694517 0.88 F2 (0.58) NPY4RNPY2RNPY5RNPY1RRAMP3
SCHEMBL29702111 0.88 F2 (0.61) NPY4RNPY2RNPY5RNPY1R
SCHEMBL29702101 0.85 F2 (0.58) NPY4RNPY2RNPY5RNPY1RTFPI
SCHEMBL18872896 0.85 AGTR1 (0.68) NPY4RNPY2RNPY5RNPY1RRAMP3
SCHEMBL30312779 0.84 NTSR1 (0.72) NPY1R
Isracidin SCHEMBL29668326 0.84 NPY2R (0.70) NPY4RNPY2RNPY5RNPY1RTFPI
SCHEMBL13234128 0.84 AGTR1 (0.69) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746852-A1 LIPID AGGREGATES FOR INTRAARTICULAR ADMINISTRATION Universität Bern (CH) 2026-05-27 — — EP claimed
US-20260124274-A1 METHODS OF INCREASING READTHROUGH OF A PREMATURE TERMINATION CODON UNIV RAMOT (IL) 2026-05-07 — — US claimed
EP-4710943-A2 TRANSFECTION COMPLEXES AND METHODS OF USING THE SAME Molecular Transfer, Inc. (US) 2026-03-18 — — EP claimed
CN-121586573-A Lipopolymers for intra-articular administration 伯尔尼大学 2026-02-27 — — CN claimed
WO-2025106551-A1 HYDROGEL COMPOSITIONS COMPRISING SYNERGISTIC ANTIMICROBIAL PEPTIDES (AMPS) AND METHODS OF MAKING SAME ROWAN UNIVERSITY (US) 2025-05-22 — — WO claimed
US-20250154525-A1 PLANT VIRUS MOVEMENT PROTEINS AND METHODS OF USING SAME MOLECULAR TRANSFER, INC. 2025-05-15 — — US claimed
WO-2025017206-A1 LIPID AGGREGATES FOR INTRAARTICULAR ADMINISTRATION Universität Bern (CH) 2025-01-23 — — WO claimed
US-12171801-B2 Compositions and related methods for controlling vector-borne diseases FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2024-12-24 — — US claimed
EP-4406963-A2 TRANSFECTION COMPLEXES AND METHODS OF USING THE SAME Molecular Transfer, Inc. (US) 2024-07-31 — — EP claimed
US-12037600-B2 Transfection complexes and methods of using the same MOLECULAR TRANSFER, INC. (US) 2024-07-16 — — US claimed
EP-4319849-A1 ANTIMICROBIAL ELUTING AIRWAY DEVICES The Children's Hospital of Philadelphia (US) 2024-02-14 — — EP claimed
US-20230270828-A1 COMPOSITION FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BICT S.R.L. (IT) 2023-08-31 — — US claimed
WO-2023141679-A1 DIMERS AND USES THEREFOR THE FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH (AU) 2023-08-03 — — WO claimed
US-20230013669-A1 Antibacterial Treatment Using a Cannabinoid and an Active Agent KREOS CAPITAL VII (UK) LIMITED (GB) 2023-01-19 — — US claimed
US-20220339187-A1 ANTIMICROBIAL PEPTIDE-SELENIUM NANOPARTICLES THE UNIVERSITY OF MELBOURNE (AU) 2022-10-27 — — US claimed
WO-2022217071-A1 ANTIMICROBIAL ELUTING AIRWAY DEVICES THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2022-10-13 — — WO claimed
EP-4065094-A1 ANTIBACTERIAL TREATMENT USING A CANNABINOID AND AN ACTIVE AGENT Botanix Pharmaceuticals Ltd (AU) 2022-10-05 — — EP claimed
EP-3129044-B1 PEPTIDOGLYCAN HYDROLASE FOR USE IN THE TREATMENT OF CHRONIC BACTERIAL INFECTIONS LYSANDO AG (LI) 2022-09-07 — — EP claimed
US-20220090141-A1 TRANSFECTION COMPLEXES AND METHODS OF USING THE SAME MOLECULAR TRANSFER, INC. 2022-03-24 — — US claimed
WO-2022058330-A1 AN ANTIMICROBIAL PEPTIDE (AMP) OR ANALOGUE THEREOF COMPRISING AT LEAST ONE PEPTIDOMIMETIC EXTENSION FOR USE AS AN ANTIMICROBIAL COMPOUND AGAINST AN INFECTIOUS DISEASE Københavns Universitet (DK) 2022-03-24 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154525-A1 PLANT VIRUS MOVEMENT PROTEINS AND METHODS OF USING SAME HDLBP, PHAX, PLTP NPY4R 4819/4885NPY2R 4857/4885NPY5R 4813/4885
US-20260124274-A1 METHODS OF INCREASING READTHROUGH OF A PREMATURE TERMINATION CODON RNMT, TRMT1L, UPF1 NPY4R 2419/4885NPY2R 3305/4885NPY5R 3256/4885
US-12037600-B2 Transfection complexes and methods of using the same TIAL1, NPC1L1, LIPA NPY4R 4136/4885NPY2R 4038/4885NPY5R 4104/4885
US-20220090141-A1 TRANSFECTION COMPLEXES AND METHODS OF USING THE SAME TIAL1, NPC1L1, LIPA NPY4R 4136/4885NPY2R 4038/4885NPY5R 4104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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