Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 6/20 | 0.40 |
| ▸ | CHRM1 known ✓ | P11229 | 6/20 | 0.40 |
| ▸ | CHRM3 known ✓ | P20309 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29212893 | 1.00 | MAPT (0.49) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL31341364 | 0.99 | MAPT (0.50) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL14192848 | 0.95 | MAPT (0.54) | MAPTMEN1LMNATHRBHTT | |
| Hydrochloric Acid SCHEMBL11043264 | 0.85 | MAPT (0.53) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL13773317 | 0.84 | MAPT (0.54) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL26220117 | 0.83 | MAPT (0.56) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL21524965 | 0.82 | PRMT1 (0.53) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL12334547 | 0.81 | PRMT1 (0.57) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL1669108 | 0.81 | MAPT (0.56) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL24767157 | 0.80 | PRMT1 (0.56) | MAPTMEN1LMNATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116908158-A | Drug mitochondrial toxicity detection method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-10-20 | — | — | CN | claimed |
| EP-3989963-A1 | CARBOCYANINE COMPOUNDS FOR TARGETING MITOCHONDRIA AND ERADICATING CANCER STEM CELLS | Lunella Biotech, Inc. (CA) | 2022-05-04 | — | — | EP | claimed |
| US-12637489-B2 | Silicon containing modified nucleotide analogs | Singular Genomics Systems, Inc. (US) | 2026-05-26 | — | — | US | disclosed |
| US-12630808-B2 | Modified archaeal family b polymerases | Singular Genomics Systems, Inc. (US) | 2026-05-19 | — | — | US | disclosed |
| US-20260125660-A1 | MODIFIED ARCHAEAL FAMILY B POLYMERASES | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-05-07 | — | — | US | disclosed |
| US-20260110028-A1 | NUCLEOTIDE ANALOGS AND USES THEREOF | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-04-23 | — | — | US | disclosed |
| US-12595508-B2 | Nucleotide cleavable linkers and uses thereof | Singular Genomics Systems, Inc. (US) | 2026-04-07 | — | — | US | disclosed |
| US-20260085299-A1 | ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-03-26 | — | — | US | disclosed |
| US-12577271-B2 | Modified nucleotides and uses thereof | Singular Genomics Systems, Inc. (US) | 2026-03-17 | — | — | US | disclosed |
| US-20260028667-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12503730-B2 | Detectable nucleotide analogues | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-12-23 | — | — | US | disclosed |
| US-20220170092-A1 | METHODS FOR LONG READ SEQUENCING | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-06-02 | — | — | US | disclosed |
| EP-3997101-A1 | NOVEL NUCLEOTIDE ANALOGUES AND METHODS FOR USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-18 | — | — | EP | disclosed |
| EP-3989963-A1 | CARBOCYANINE COMPOUNDS FOR TARGETING MITOCHONDRIA AND ERADICATING CANCER STEM CELLS | Lunella Biotech, Inc. (CA) | 2022-05-04 | — | — | EP | disclosed |
| US-20220127299-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | LG ELECTRONICS INC. (KR) | 2022-04-28 | — | — | US | disclosed |
| US-20220119780-A1 | ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-04-21 | — | — | US | disclosed |
| US-20220119779-A1 | MODIFIED PYROCOCCUS POLYMERASES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-04-21 | — | — | US | disclosed |
| WO-2022072374-A1 | LIGHT-CONTROLLED BIOORTHOGONAL TETRAZINE LIGATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-07 | — | — | WO | disclosed |
| CN-114173773-A | Carbocyanine compounds for targeting mitochondria and eradicating cancer stem cells | 卢内拉生物技术有限公司 | 2022-03-11 | — | — | CN | disclosed |
| US-11266673-B2 | Nucleotide derivatives and methods of use thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630808-B2 | Modified archaeal family b polymerases | SSU72, POLB, POLQ | CHRM2 4476/4885CHRM1 4295/4885CHRM3 4687/4885 |
| US-12595508-B2 | Nucleotide cleavable linkers and uses thereof | NSUN2, CCRL2, NOP2 | CHRM2 2094/4885CHRM1 2110/4885CHRM3 644/4885 |
| US-12577271-B2 | Modified nucleotides and uses thereof | NUDT1, NSUN2, CCRL2 | CHRM2 1617/4885CHRM1 1653/4885CHRM3 489/4885 |
| US-12637489-B2 | Silicon containing modified nucleotide analogs | NSUN2, POLR2H, POLH | CHRM2 2620/4885CHRM1 2726/4885CHRM3 755/4885 |
| US-20260110028-A1 | NUCLEOTIDE ANALOGS AND USES THEREOF | POLL, POLB, POLN | CHRM2 4745/4885CHRM1 4561/4885CHRM3 4650/4885 |
| US-20220127299-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | NUDT21, CPSF7, DCLRE1A | CHRM2 4871/4885CHRM1 4853/4885CHRM3 4662/4885 |
| US-20260085299-A1 | ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF | POLB, POLM, POLRMT | CHRM2 4022/4885CHRM1 3851/4885CHRM3 4003/4885 |
| US-20260028667-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | POLN, NSUN2, POLL | CHRM2 4256/4885CHRM1 3115/4885CHRM3 3490/4885 |
| US-20260125660-A1 | MODIFIED ARCHAEAL FAMILY B POLYMERASES | DNMT3A, POLB, POLM | CHRM2 4509/4885CHRM1 3939/4885CHRM3 4592/4885 |
| US-12503730-B2 | Detectable nucleotide analogues | NT5C3B, NUDT1, RNGTT | CHRM2 4877/4885CHRM1 4861/4885CHRM3 4615/4885 |
| US-11266673-B2 | Nucleotide derivatives and methods of use thereof | POLRMT, NSUN2, NUDT1 | CHRM2 4881/4885CHRM1 4872/4885CHRM3 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.