Taxagifine

Taxagifine

SCHEMBL29520283

C=C1[C@@H](OC(=O)/C=C/c2ccccc2)C[C@H](OC(C)=O)[C@@]2(C)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@]3(O)[C@@]4(C)CO[C@]3(C)C(=O)C[C@H]4[C@@H](OC(C)=O)[C@H]12

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 18/20 0.40
NLRP3 Q96P20 1/20 0.39
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taxagifine SCHEMBL28964410 1.00 ABCB1 (0.40) ABCB1NLRP3CYP2C19
SCHEMBL28981503 0.87 ABCB1 (0.42) ABCB1
SCHEMBL30367067 0.87 ABCB1 (0.42) ABCB1
SCHEMBL44183 0.85 ABCB1 (0.41) ABCB1NLRP3
SCHEMBL29425006 0.79 NLRP3 (0.38) ABCB1NLRP3CYP2C19
SCHEMBL44567 0.66 NLRP3 (0.43) ABCB1NLRP3CYP2C19
SCHEMBL31384147 0.66 NLRP3 (0.43) ABCB1NLRP3CYP2C19
Taxuspine J SCHEMBL32665717 0.65 NLRP3 (0.41) ABCB1NLRP3CYP2C19
Taxuspine A SCHEMBL31565642 0.62 ABCB1 (0.41) ABCB1NLRP3
SCHEMBL21892003 0.57 CYP2C19 (0.65) ABCB1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3716765-B1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2026-01-07 EP disclosed
US-12480137-B2 Plants having increased tolerance to herbicides BASF SE (DE) 2025-11-25 US disclosed
EP-4633362-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF Agricultural Solutions US LLC (US) 2025-10-22 EP disclosed
EP-3247200-B1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2025-10-15 EP disclosed
US-20250215447-A1 Plants Having Increased Tolerance to Herbicides BASF SE (DE) 2025-07-03 US disclosed
US-12338446-B2 Plants having increased tolerance to herbicides BASF Agro B.V. (NL) 2025-06-24 US disclosed
US-20250197881-A1 HERBICIDE-TOLERANT PLANTS BASF AGROCHEMICAL PRODUCTS BV (NL) 2025-06-19 US disclosed
EP-4549569-A2 HERBICIDE-TOLERANT PLANTS BASF Agrochemical Products, B.V. (NL) 2025-05-07 EP disclosed
US-20250127169-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF AGRICULTURAL SOLUTIONS US LLC 2025-04-24 US disclosed
US-20250122523-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2025-04-17 US disclosed
US-20220361495-A1 METHOD FOR CONTROLLING PPO RESISTANT WEEDS BASF SE (DE) 2022-11-17 US disclosed
US-11499162-B2 Plants having increased tolerance to herbicides BASF SE (DE) 2022-11-15 US disclosed
US-20220348951-A1 HERBICIDE TOLERANT PLANTS BASF SE (DE) 2022-11-03 US disclosed
US-11479786-B2 Plants having increased tolerance to herbicides BASF SE (DE) 2022-10-25 US disclosed
US-20220333127-A1 Plants Having Increased Tolerance to Herbicides BASF SE (DE) 2022-10-20 US disclosed
US-20220315944-A1 Plants Having Increased Tolerance to Herbicides BASF AGRO BV (NL) 2022-10-06 US disclosed
US-11419337-B2 Method for controlling PPO resistant weeds BASF SE (DE) 2022-08-23 US disclosed
WO-2022164870-A1 RECOMBINANT POLYPRENOL DIPHOSPHATE SYNTHASES CB THERAPEUTICS, INC. (US) 2022-08-04 WO disclosed
US-11365426-B2 Plants having increased tolerance to herbicides BASF SE (DE) 2022-06-21 US disclosed
US-11306322-B2 Plants having increased tolerance to herbicides BASF Agro B.V. (NL) 2022-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122523-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES PPOX, PNPO, PAOX ABCB1 537/4885NLRP3 4710/4885CYP2C19 680/4885
US-20220315944-A1 Plants Having Increased Tolerance to Herbicides PPOX, PNPO, PAOX ABCB1 536/4885NLRP3 4673/4885CYP2C19 664/4885
US-11479786-B2 Plants having increased tolerance to herbicides PPOX, PNPO, PAOX ABCB1 537/4885NLRP3 4710/4885CYP2C19 680/4885
US-11499162-B2 Plants having increased tolerance to herbicides PNKP, TARS2, CIP2A ABCB1 1945/4885NLRP3 4675/4885CYP2C19 4559/4885
US-11306322-B2 Plants having increased tolerance to herbicides PPOX, PNPO, PAOX ABCB1 536/4885NLRP3 4673/4885CYP2C19 664/4885
US-12480137-B2 Plants having increased tolerance to herbicides CES2, PFAS, RNGTT ABCB1 293/4885NLRP3 4675/4885CYP2C19 2276/4885
US-20250127169-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES PPOX, PNPO, PAOX ABCB1 537/4885NLRP3 4710/4885CYP2C19 680/4885
US-20250197881-A1 HERBICIDE-TOLERANT PLANTS ACACB, ACACA, ACAT1 ABCB1 1206/4885NLRP3 4726/4885CYP2C19 1354/4885
US-11419337-B2 Method for controlling PPO resistant weeds PPOX, PNPO, NOTUM ABCB1 420/4885NLRP3 3641/4885CYP2C19 329/4885
US-20220333127-A1 Plants Having Increased Tolerance to Herbicides CES2, PFAS, RNGTT ABCB1 293/4885NLRP3 4675/4885CYP2C19 2276/4885
US-20220361495-A1 METHOD FOR CONTROLLING PPO RESISTANT WEEDS PPOX, PNPO, NOTUM ABCB1 420/4885NLRP3 3641/4885CYP2C19 329/4885
US-11365426-B2 Plants having increased tolerance to herbicides CES2, PFAS, RNGTT ABCB1 293/4885NLRP3 4675/4885CYP2C19 2276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.