SCHEMBL2954176

SCHEMBL2954176

CC(C)Cn1c(=O)[nH]c(=O)c2[nH]c(N3CCCC3)nc21

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 3/20 0.51
MEN1 O00255 6/20 0.45
KMT2A Q03164 6/20 0.45
PDE5A O76074 1/20 0.41
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 4/20 0.40
ADORA2A P29274 1/20 0.40
ADORA2B P29275 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
PDE2A O00408 1/20 0.39
PDE1A P54750 1/20 0.39
PDE1B Q01064 1/20 0.39
PDE1C Q14123 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7621510 0.81 ADORA1 (0.62) ADORA1MEN1KMT2AKDM4EALDH1A1
SCHEMBL6363706 0.79 ADORA1 (0.48) ADORA1MEN1KMT2AKDM4EALDH1A1
SCHEMBL7624397 0.78 ADORA1 (0.49) ADORA1MEN1KMT2APDE5AALDH1A1
SCHEMBL5646 0.77 PDE2A (0.61) ADORA1MEN1KMT2APDE5AKDM4E
SCHEMBL10309248 0.76 MEN1 (0.65) ADORA1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL19583186 0.76 KDM4E (0.43) ADORA1MEN1KMT2APDE5AKDM4E
SCHEMBL4796596 0.75 PDE1A (0.46) ADORA1MEN1KMT2APDE5AKDM4E
SCHEMBL6234430 0.74 PDE5A (0.64) MEN1KMT2APDE5AKDM4EALDH1A1
SCHEMBL272517 0.74 KDM4E (0.41) ADORA1MEN1KMT2APDE5AKDM4E
SCHEMBL2053839 0.73 PDE5A (0.42) ADORA1MEN1KMT2APDE5AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3900712-A1 GPCR HETEROMER INHIBITORS AND USES THEREOF GPCR Therapeutics, Inc. (KR) 2021-10-27 EP claimed
EP-3727371-A1 GPCR HETEROMER INHIBITORS AND USES THEREOF GPCR Therapeutics, Inc. (KR) 2020-10-28 EP claimed
CN-111741752-A GPCR heteromer inhibitors and uses thereof GPCR治疗公司 2020-10-02 CN claimed
US-9555037-B2 Method of using vasoconstrictive agents during energy-based tissue therapy COVIDIEN AG 2017-01-31 US claimed
US-20160151374-A1 METHOD OF USING VASOCONSTRICTIVE AGENTS DURING ENERGY-BASED TISSUE THERAPY SHERWOOD SERVICES AG (CH) 2016-06-02 US claimed
US-9271985-B2 Method of using vasoconstrictive agents during energy-based tissue therapy COVIDIEN AG (CH) 2016-03-01 US claimed
US-20150164903-A1 METHOD OF USING VASOCONSTRICTIVE AGENTS DURING ENERGY-BASED TISSUE THERAPY SHERWOOD SERVICES AG (CH) 2015-06-18 US claimed
US-7767686-B2 Method of using adenosine receptor blockers during tissue ablation COVIDIEN AG (CH) 2010-08-03 US claimed
US-20080275068-A1 administering a vasoconstrictive agent such as an adenosine receptor antagonist ( 1,3-dipropyl-8-cyclopentylxanthine, 8-(3-Chlorostyryl)caffeine, 6-carboxy-methyl-5,9-dihydro-9-methyl-2-phenyl-[1,2,4]-triazolo[5,1-a][2,7]naphthyridine) to the mammal to increases the size of the coagulation zone COVIDIEN AG (CH) 2008-11-06 US claimed
US-20070207979-A1 Method of using adenosine receptor blockers during tissue ablation SHERWOOD SERVICES AG 2007-09-06 US claimed
US-20070208042-A1 Method of using vasoconstrictive agents during energy-based tissue therapy SHERWOOD SERVICES AG 2007-09-06 US claimed
US-12585199-B2 Overlay correction method, and exposure method and semiconductor device manufacturing method including overlay correction method SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-03-24 US disclosed
US-20250387363-A1 LIQUID EPINEPHRINE PRODRUG FORMULATIONS AND LIQUID EPINEPHRINE FORMULATIONS INSIGNIS THERAPEUTICS INC (US) 2025-12-25 US disclosed
US-20250316979-A1 POE PD Redundant System MICROCHIP TECHNOLOGY INCORPORATED (US) 2025-10-09 US disclosed
US-12321091-B2 Device and method for determining placements of pattern elements of a reflective photolithographic mask in the operating environment thereof CARL ZEISS SMT GMBH (DE) 2025-06-03 US disclosed
US-7767686-B2 Method of using adenosine receptor blockers during tissue ablation COVIDIEN AG (CH) 2010-08-03 US disclosed
US-20090136460-A1 USE OF ADENOSINE RECEPTOR LIGANDS TO PROMOTE CELL ADHESION IN CELL-BASED THERAPIES VANDERBILT UNIVERSITY 2009-05-28 US disclosed
US-20080275068-A1 administering a vasoconstrictive agent such as an adenosine receptor antagonist ( 1,3-dipropyl-8-cyclopentylxanthine, 8-(3-Chlorostyryl)caffeine, 6-carboxy-methyl-5,9-dihydro-9-methyl-2-phenyl-[1,2,4]-triazolo[5,1-a][2,7]naphthyridine) to the mammal to increases the size of the coagulation zone COVIDIEN AG (CH) 2008-11-06 US disclosed
US-20070207979-A1 Method of using adenosine receptor blockers during tissue ablation SHERWOOD SERVICES AG 2007-09-06 US disclosed
US-20070208042-A1 Method of using vasoconstrictive agents during energy-based tissue therapy SHERWOOD SERVICES AG 2007-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070207979-A1 Method of using adenosine receptor blockers during tissue ablation ADORA2A, ADORA2B, ADORA3 ADORA1 4/4885MEN1 2573/4885KMT2A 3150/4885
US-20070208042-A1 Method of using vasoconstrictive agents during energy-based tissue therapy PLAT, TEK, PLG ADORA1 503/4885MEN1 2440/4885KMT2A 3816/4885
US-12585199-B2 Overlay correction method, and exposure method and semiconductor device manufacturing method including overlay correction method RHOA, SRMS, SORBS1 ADORA1 3985/4885MEN1 3344/4885KMT2A 627/4885
US-20150164903-A1 METHOD OF USING VASOCONSTRICTIVE AGENTS DURING ENERGY-BASED TISSUE THERAPY PLAT, TEK, PLG ADORA1 503/4885MEN1 2440/4885KMT2A 3816/4885
US-20160151374-A1 METHOD OF USING VASOCONSTRICTIVE AGENTS DURING ENERGY-BASED TISSUE THERAPY PLAT, TEK, PLG ADORA1 503/4885MEN1 2440/4885KMT2A 3816/4885
US-20080275068-A1 administering a vasoconstrictive agent such as an adenosine receptor antagonist ( 1,3-dipropyl-8-cyclopentylxanthine, 8-(3-Chlorostyryl)caffeine, 6-carboxy-methyl-5,9-dihydro-9-methyl-2-phenyl-[1,2,4]-triazolo[5,1-a][2,7]naphthyridine) to the mammal to increases the size of the coagulation zone ADORA2A, ADORA1, ADORA3 ADORA1 2/4885MEN1 2712/4885KMT2A 2041/4885
US-20250387363-A1 LIQUID EPINEPHRINE PRODRUG FORMULATIONS AND LIQUID EPINEPHRINE FORMULATIONS ADRB3, ADRB2, ADRB1 ADORA1 126/4885MEN1 1013/4885KMT2A 4660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.