Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548514 | 0.84 | GPR119 (0.44) | SCD5CYP11B2HDAC1HDAC2SPR | |
| SCHEMBL29548305 | 0.78 | SPR (0.40) | SCD5CYP11B2SPRRETGPR119 | |
| SCHEMBL29548540 | 0.76 | RET (0.39) | SCD5HDAC1HDAC2SPRRET | |
| SCHEMBL29548391 | 0.68 | SPR (0.40) | SCD5CYP11B2SPRRETALDH1A1 | |
| SCHEMBL29548481 | 0.68 | SPR (0.37) | SCD5CYP11B2SPRRET | |
| SCHEMBL29548473 | 0.68 | SPR (0.37) | SCD5CYP11B2SPRMAPTRET | |
| SCHEMBL29548733 | 0.68 | RET (0.41) | SPRRETGPR119 | |
| SCHEMBL29548310 | 0.66 | DRD2 (0.39) | JAK2JAK1CAMKK1CAMKK2 | |
| SCHEMBL31487947 | 0.66 | MAPT (0.46) | JAK2JAK1MAPTRETGPR119 | |
| SCHEMBL31487838 | 0.64 | HTT (0.53) | JAK2MAPTALDH1A1TSHRGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |