SCHEMBL29565282

SCHEMBL29565282

CC[C@H](C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CS)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)[C@@H](C)CC

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 15/20 0.60
▸ CALCR P30988 3/20 0.59
▸ PTH1R Q03431 1/20 0.58
▸ GCGR P47871 1/20 0.55
▸ GIPR P48546 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29973140 0.98 CALCR (0.61) GLP1RCALCRPTH1R
SCHEMBL31376429 0.98 PTH1R (0.60) GLP1RCALCRPTH1RGCGRGIPR
SCHEMBL29973297 0.97 GLP1R (0.62) GLP1R
SCHEMBL29973649 0.93 GLP1R (0.61) GLP1RPTH1RGCGRGIPR
SCHEMBL29973471 0.92 GLP1R (0.60) GLP1R
SCHEMBL29921851 0.91 PTH1R (0.65) GLP1RPTH1RGCGRGIPR
SCHEMBL30524411 0.90 GLP1R (0.59) GLP1RGCGRGIPR
SCHEMBL29720268 0.90 CALCR (0.59) GLP1RCALCRPTH1R
SCHEMBL29973282 0.89 EDNRA (0.56) GLP1R
SCHEMBL31574195 0.89 GLP1R (0.63) GLP1RCALCRPTH1RGCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137691-A1 WB3 FOR ANESTHESIA AND TREATING PAIN PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-05-21 — — US disclosed
US-20260109760-A1 NEUTRALIZING ANTIBODIES TO HUMAN ENDOTHELIN FATHER FLANAGANS BOYS HOME DOING BUSINESS AS BOYS TOWN NATIONAL RES HOSPITAL (US) 2026-04-23 — — US disclosed
US-12577300-B2 Neutralizing antibodies to human endothelin Father Flanagan's Boys' Home Business (US) 2026-03-17 — — US disclosed
US-20260060221-A1 METHOD FOR PRODUCING NONHUMAN PRIMATE ANIMAL MODEL OF CEREBRAL INFARCTION AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CEREBRAL INFARCTION ASTELLAS PHARMA INC. (JP) 2026-03-05 — — US disclosed
US-20260021061-A1 ARIADNE AND ANALOGS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROMUSCLAR DISORDERS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2026-01-22 — — US disclosed
US-20250353808-A1 5-METHOXYMETHYL AND 5-HYDROXYMETHYL PHENETHYLAMINES 2A BIOSCIENCES, INC. 2025-11-20 — — US disclosed
US-12458624-B2 Deuterium-enriched substituted phenoxyphenyl acetic acids and acylsulfonamides DHANOA DALJIT SINGH (US) 2025-11-04 — — US disclosed
WO-2025137511-A1 INTEGRATED AND ITERATIVE METHODS FOR DESIGNING, IDENTIFYING AND OPTIMIZING LASSO PEPTIDES LASSOGEN, INC. (US) 2025-06-26 — — WO disclosed
EP-4548757-A1 METHOD FOR PRODUCING NON-HUMAN PRIMATE MODEL OF CEREBRAL INFARCTION AND PHARMACEUTICAL COMPOSITION FOR TREATING CEREBRAL INFARCTION Astellas Pharma, Inc. (JP) 2025-05-07 — — EP disclosed
US-12240816-B2 Deuterated compounds and uses thereof ALDEYRA THERAPEUTICS, INC. (US) 2025-03-04 — — US disclosed
WO-2023192853-A2 LASSO PEPTIDES AS ENDOTHELIN B RECEPTOR ANTAGONISTS LASSOGEN, INC. (US) 2023-10-05 — — WO disclosed
EP-4046995-B1 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS SUNOVION PHARMACEUTICALS INC (US) 2023-09-13 — — EP disclosed
US-20230174491-A1 DEUTERATED COMPOUNDS AND USES THEREOF ALDEYRA THERAPEUTICS, INC. 2023-06-08 — — US disclosed
US-20230039319-A1 DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES DHANOA DALJIT SINGH (US) 2023-02-09 — — US disclosed
US-11459300-B2 Deuterated compounds and uses thereof ALDEYRA THERAPEUTICS, INC. (US) 2022-10-04 — — US disclosed
EP-4046995-A1 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS Sunovion Pharmaceuticals Inc. (US) 2022-08-24 — — EP disclosed
EP-3256466-B9 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS SUNOVION PHARMACEUTICALS INC (US) 2022-07-27 — — EP disclosed
US-20220195034-A1 NEUTRALIZING ANTIBODIES TO HUMAN ENDOTHELIN FATHER FLANAGAN'S BOYS' HOME DOING BUSINESS AS BOYS TOWN NATIONAL RESEARCH HOSPITAL 2022-06-23 — — US disclosed
US-20220185799-A1 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS SUNOVION PHARMACEUTICALS INC. (US) 2022-06-16 — — US disclosed
EP-3256466-B1 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS SUNOVION PHARMACEUTICALS INC (US) 2022-04-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230039319-A1 DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES AGTR2, AGTR1, EDNRA GLP1R 108/4885CALCR 1207/4885PTH1R 493/4885
US-20260060221-A1 METHOD FOR PRODUCING NONHUMAN PRIMATE ANIMAL MODEL OF CEREBRAL INFARCTION AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CEREBRAL INFARCTION FABP7, NES, VEGFA GLP1R 1723/4885CALCR 1156/4885PTH1R 2984/4885
US-20260109760-A1 NEUTRALIZING ANTIBODIES TO HUMAN ENDOTHELIN ETV1, CDR2, IGLV6-57 GLP1R 2059/4885CALCR 448/4885PTH1R 59/4885
US-12577300-B2 Neutralizing antibodies to human endothelin IGLV6-57, ETV1, VEGFA GLP1R 1997/4885CALCR 602/4885PTH1R 78/4885
US-20260137691-A1 WB3 FOR ANESTHESIA AND TREATING PAIN WNT3, TRPV3, ADRB3 GLP1R 3066/4885CALCR 1169/4885PTH1R 1547/4885
US-20250353808-A1 5-METHOXYMETHYL AND 5-HYDROXYMETHYL PHENETHYLAMINES HTR5A, PNMT, HTR6 GLP1R 1324/4885CALCR 2238/4885PTH1R 3248/4885
US-20220185799-A1 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS CNR1, HCRTR1, CNR2 GLP1R 3109/4885CALCR 3640/4885PTH1R 4349/4885
US-20230174491-A1 DEUTERATED COMPOUNDS AND USES THEREOF ALDH1A2, SSB, DBH GLP1R 3683/4885CALCR 4543/4885PTH1R 3498/4885
US-12240816-B2 Deuterated compounds and uses thereof ALDH1A2, SSB, DBH GLP1R 3683/4885CALCR 4543/4885PTH1R 3498/4885
US-12458624-B2 Deuterium-enriched substituted phenoxyphenyl acetic acids and acylsulfonamides AGTR2, AGTR1, EDNRA GLP1R 108/4885CALCR 1207/4885PTH1R 493/4885
US-11459300-B2 Deuterated compounds and uses thereof ALDH1A2, SSB, DBH GLP1R 3683/4885CALCR 4543/4885PTH1R 3498/4885
US-20260021061-A1 ARIADNE AND ANALOGS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROMUSCLAR DISORDERS ATXN2, HCRTR2, CDR2 GLP1R 3215/4885CALCR 488/4885PTH1R 3833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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