Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATP4A | P20648 | 1/20 | 0.31 |
| ▸ | ATP4B | P51164 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 4/20 | 0.30 |
| ▸ | ACHE | P22303 | 3/20 | 0.30 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16329608 | 0.92 | SLC6A1 (0.34) | KCNH2SLC6A1SLC6A11PBRM1 | |
| SCHEMBL27050962 | 0.92 | SLC6A1 (0.34) | KCNH2SLC6A1SLC6A11PBRM1 | |
| SCHEMBL2820572 | 0.92 | SLC6A1 (0.34) | KCNH2SLC6A1SLC6A11PBRM1 | |
| SCHEMBL25764740 | 0.92 | SLC6A1 (0.34) | KCNH2SLC6A1SLC6A11PBRM1 | |
| SCHEMBL2472575 | 0.89 | SLC6A11 (0.35) | KCNH2MEN1KMT2ASLC6A1SLC6A11 | |
| SCHEMBL17166451 | 0.88 | ALDH1A1 (0.33) | MEN1KMT2ASLC6A11 | |
| SCHEMBL14005138 | 0.87 | KIF11 (0.32) | KCNH2SLC6A1SLC6A11 | |
| SCHEMBL31688441 | 0.85 | SLC6A1 (0.33) | SLC6A1SLC6A11PBRM1 | |
| SCHEMBL19448739 | 0.85 | SLC6A1 (0.33) | SLC6A1SLC6A11 | |
| SCHEMBL30802594 | 0.85 | SLC6A1 (0.33) | SLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11358937-B2 | Reagents based on a tertiary amine backbone to introduce chemical functionality in nucleic acids and sequence-controlled polymers | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2022-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11358937-B2 | Reagents based on a tertiary amine backbone to introduce chemical functionality in nucleic acids and sequence-controlled polymers | ADAR, SPOUT1, RNGTT | MAOA 2701/4885MAOB 2449/4885PLA2G2A 3595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.