Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.69 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.52 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.52 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.52 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846278 | 0.85 | ALDH1A1 (0.74) | ALDH1A1HIF1ASUMO2SUMO1SENP7 | |
| SCHEMBL29350187 | 0.85 | ALDH1A1 (0.74) | ALDH1A1HIF1ASUMO2SUMO1SENP7 | |
| SCHEMBL29399244 | 0.83 | ALDH1A1 (0.65) | ALDH1A1HIF1ASUMO2SUMO1SENP7 | |
| SCHEMBL6846279 | 0.81 | HIF1A (1.00) | ALDH1A1HIF1ASUMO2SUMO1SENP7 | |
| SCHEMBL8816124 | 0.81 | HIF1A (1.00) | ALDH1A1HIF1ASUMO2SUMO1SENP7 | |
| SCHEMBL4068193 | 0.81 | HIF1A (1.00) | ALDH1A1HIF1ASUMO2SUMO1SENP7 | |
| SCHEMBL10622991 | 0.81 | HIF1A (0.98) | ALDH1A1HIF1ASUMO2SUMO1SENP7 | |
| SCHEMBL8947349 | 0.78 | ALDH1A1 (0.87) | ALDH1A1HIF1ASUMO2SUMO1SENP7 | |
| SCHEMBL133302 | 0.78 | ALDH1A1 (0.65) | ALDH1A1HIF1ASUMO2SUMO1SENP7 | |
| SCHEMBL15424240 | 0.77 | HIF1A (0.76) | ALDH1A1HIF1ASUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024187194-A2 | PHOTOCLICK CHEMISTRY OF SILK FOR TEMPORARY UV TATTOOS | TRUSTEES OF TUFTS COLLEGE (US) | 2024-09-12 | — | — | WO | disclosed |
| WO-2024097977-A1 | SILK NANOPARTICLE SYNTHESIS: TUNING SIZE, DISPERSITY, AND SURFACE CHEMISTRY FOR DRUG DELIVERY | TRUSTEES OF TUFTS COLLEGE (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024014508-A1 | MARKER COMPOSITION FOR SKIN, AND APPLICATION TOOL FOR SAME | 三菱鉛筆株式会社 | 2024-01-18 | — | — | WO | disclosed |
| WO-2022091971-A1 | MARKER COMPOSITION FOR SKIN | 三菱鉛筆株式会社 | 2022-05-05 | — | — | WO | disclosed |