Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18335912 | 0.95 | NOS1 (0.31) | NOS1NOS2HTT | |
| SCHEMBL24361005 | 0.79 | — | — | |
| SCHEMBL24361009 | 0.78 | ALDH1A1 (0.33) | HTT | |
| SCHEMBL124837 | 0.75 | DGAT1 (0.34) | HTT | |
| SCHEMBL16139995 | 0.75 | CES2 (0.43) | HTT | |
| Bicarbonate SCHEMBL17529921 | 0.74 | HTT (0.42) | HTT | |
| SCHEMBL13645226 | 0.74 | — | — | |
| Potassium Ion SCHEMBL18335913 | 0.73 | — | — | |
| SCHEMBL24361123 | 0.73 | ALDH1A1 (0.40) | HTT | |
| SCHEMBL22235126 | 0.73 | ARG1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423758-B | Antibacterial compounds | 爱尔兰詹森科学公司 | 2025-05-27 | — | — | CN | disclosed |
| US-20240199611-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2024-06-20 | — | — | US | disclosed |
| EP-4028399-B1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2024-02-14 | — | — | EP | disclosed |
| EP-4308239-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2024-01-24 | — | — | EP | disclosed |
| CN-117396475-A | Antibacterial compounds | 爱尔兰詹森科学公司 | 2024-01-12 | — | — | CN | disclosed |
| US-20220340564-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN-CILAG (FR) | 2022-10-27 | — | — | US | disclosed |
| WO-2022194803-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-09-22 | — | — | WO | disclosed |
| EP-4028399-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-07-20 | — | — | EP | disclosed |
| CN-114423758-A | Antibacterial compounds | 爱尔兰詹森科学公司 | 2022-04-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199611-A1 | ANTIBACTERIAL COMPOUNDS | FDPS, MT-ND4, NDUFS3 | NOS1 1335/4885NOS2 1396/4885HTT 3396/4885 |
| US-20220340564-A1 | ANTIBACTERIAL COMPOUNDS | FDPS, SQOR, NDUFS3 | NOS1 1496/4885NOS2 1333/4885HTT 3111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.