Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30070449 | 0.89 | MAOA (0.37) | KDM4EALDH1A1HSD17B1HSD17B10ABCC9 | |
| SCHEMBL19949080 | 0.89 | MAOA (0.37) | KDM4EALDH1A1HSD17B1HSD17B10ABCC9 | |
| SCHEMBL1339423 | 0.79 | NOTUM (0.44) | KDM4EALDH1A1HPGDHSD17B1CASP1 | |
| SCHEMBL30666511 | 0.79 | NOTUM (0.44) | KDM4EALDH1A1HPGDHSD17B1CASP1 | |
| SCHEMBL30667056 | 0.76 | NOTUM (0.47) | KDM4EALDH1A1HPGDHSD17B1CASP1 | |
| SCHEMBL9274349 | 0.76 | NOTUM (0.47) | KDM4EALDH1A1HPGDHSD17B1CASP1 | |
| SCHEMBL31392216 | 0.76 | CASP1 (0.41) | KDM4EALDH1A1HPGDHSD17B1CASP1 | |
| SCHEMBL20190017 | 0.76 | HSD17B1 (0.44) | KDM4EALDH1A1HPGDHSD17B1CASP1 | |
| SCHEMBL1512616 | 0.76 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B1CASP1 | |
| SCHEMBL15287071 | 0.76 | CASP1 (0.41) | KDM4EALDH1A1HPGDHSD17B1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731961-B2 | Phenyl propionic acid derivatives and uses thereof | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2023-08-22 | — | — | US | disclosed |
| US-11731961-B2 | Phenyl propionic acid derivatives and uses thereof | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2023-08-22 | — | — | US | disclosed |
| US-11731961-B2 | Phenyl propionic acid derivatives and uses thereof | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2023-08-22 | — | — | US | disclosed |
| EP-3555076-B1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | IL DONG PHARMA (KR) | 2023-04-05 | — | — | EP | disclosed |
| CN-110049984-B | Phenylpropionic acid derivatives and use thereof | 日东制药株式会社 | 2022-11-15 | — | — | CN | disclosed |
| US-20220112185-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-14 | — | — | US | disclosed |
| US-20220064154-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | ILDONG PHARMACEUTICAL CO, LTD. (KR) | 2022-03-03 | — | — | US | disclosed |
| US-11225472-B2 | Phenyl propionic acid derivatives and uses thereof | IL DONG PHARMACEUTICAL CO., LTD. | 2022-01-18 | — | — | US | disclosed |
| WO-2021027943-A1 | PYRIMIDINOPYRIDAZINONE DERIVATIVE AND MEDICAL USE THEREOF | 正大天晴药业集团南京顺欣制药有限公司 | 2021-02-18 | — | — | WO | disclosed |
| US-20200223833-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | IL DONG PHARMACEUTICAL CO., LTD. (KR) | 2020-07-16 | — | — | US | disclosed |
| WO-2013062892-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2013-05-02 | — | — | WO | disclosed |
| US-20120277190-A1 | PRODRUGS OF COMPOUNDS THAT INHIBIT TRPV1 RECEPTOR | ABBVIE INC. | 2012-11-01 | — | — | US | disclosed |
| US-8232309-B2 | Prodrugs of compounds that inhibit TRPV1 receptor | ABBOTT LABORATORIES (US) | 2012-07-31 | — | — | US | disclosed |
| CN-102516176-A | Indazole derivatives that inhibit TRPVL receptor | ABBOTT LAB | 2012-06-27 | — | — | CN | disclosed |
| WO-2012058134-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | disclosed |
| EP-2427444-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | Merck Sharp & Dohme Corp. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129379-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-20100286123-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME LLC | 2010-11-11 | — | — | US | disclosed |
| CN-101365684-A | Indazole derivatives inhibiting TRPV1 receptor | ABBOTT LAB (US) | 2009-02-11 | — | — | CN | disclosed |
| US-20070099954-A1 | Prodrugs of compounds that inhibit TRPV1 receptor | ABBVIE INC. | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220064154-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | GPR119, GPR65, GPR55 | KDM4E 3484/4885ALDH1A1 872/4885HPGD 2338/4885 |
| US-11225472-B2 | Phenyl propionic acid derivatives and uses thereof | GPR119, GPR55, GPR65 | KDM4E 3561/4885ALDH1A1 755/4885HPGD 1872/4885 |
| US-20120277190-A1 | PRODRUGS OF COMPOUNDS THAT INHIBIT TRPV1 RECEPTOR | TRPV1, TRPV3, TRPA1 | KDM4E 3148/4885ALDH1A1 583/4885HPGD 274/4885 |
| US-20220112185-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | GPR119, GPR55, GPR65 | KDM4E 3215/4885ALDH1A1 698/4885HPGD 2362/4885 |
| US-20200223833-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | GPR119, GLP1R, GPR65 | KDM4E 3459/4885ALDH1A1 806/4885HPGD 2097/4885 |
| US-20100286123-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | KCNJ11, KCNJ1, KCNJ2 | KDM4E 1977/4885ALDH1A1 1376/4885HPGD 1579/4885 |
| US-20070099954-A1 | Prodrugs of compounds that inhibit TRPV1 receptor | TRPV1, TRPV3, TRPA1 | KDM4E 3148/4885ALDH1A1 583/4885HPGD 274/4885 |
| US-11731961-B2 | Phenyl propionic acid derivatives and uses thereof | GPR119, GPR65, GPR55 | KDM4E 3730/4885ALDH1A1 731/4885HPGD 2009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.