Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.60 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576359 | 1.00 | ALDH1A1 (0.71) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL988798 | 1.00 | ALDH1A1 (0.71) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL4317761 | 0.92 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL2139678 | 0.92 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL2139676 | 0.92 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL21457264 | 0.89 | TP53 (0.57) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL21457267 | 0.89 | TP53 (0.57) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL20278911 | 0.88 | ALDH1A1 (0.74) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL8998886 | 0.88 | ALDH1A1 (0.74) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL8998890 | 0.88 | ALDH1A1 (0.74) | ALDH1A1MAPTKDM4EPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | claimed |
| US-20120156270-A1 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | L'OREAL (FR) | 2012-06-21 | — | — | US | disclosed |
| US-20120156270-A1 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | L'OREAL (FR) | 2012-06-21 | — | — | US | disclosed |
| US-20120156270-A1 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | L'OREAL (FR) | 2012-06-21 | — | — | US | disclosed |
| WO-2011003771-A2 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | L'OREAL (FR) | 2011-01-13 | — | — | WO | disclosed |
| US-20100172858-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER | L'OREAL S.A. (FR) | 2010-07-08 | — | — | US | disclosed |
| US-20100172858-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER | L'OREAL S.A. (FR) | 2010-07-08 | — | — | US | disclosed |
| US-20100172858-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER | L'OREAL S.A. (FR) | 2010-07-08 | — | — | US | disclosed |
| EP-2124874-A2 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER | L'Oreal (FR) | 2009-12-02 | — | — | EP | disclosed |
| US-7621966-B2 | Cosmetic composition comprising at least one pigment and/or at least one filler surface-treated beforehand with at least one organic agent and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2009-11-24 | — | — | US | disclosed |
| US-20060276515-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-12-07 | — | — | US | disclosed |
| WO-2006121719-A2 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL, GMBH (DE) | 2006-11-16 | — | — | WO | disclosed |
| US-20060233731-A1 | Use, for the cosmetic treatment of keratin materials, of a film-forming composition comprising an electrophilic monomer and a non-silicone polymer, conferring a soft coating | L'OREAL S.A. (FR) | 2006-10-19 | — | — | US | disclosed |
| US-20060179587-A1 | Dyeing composition comprising a specific pigment and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2006-08-17 | — | — | US | disclosed |
| US-20060115445-A1 | Compositions for treating keratin materials comprising electrophilic monomers and liquid crystal agents | L'OREAL S.A. (FR) | 2006-06-01 | — | — | US | disclosed |
| US-20060088493-A1 | Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060088488-A1 | Dyeing composition comprising a mixture of at least one pigment and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060083706-A1 | Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060083762-A1 | Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060078522-A1 | Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt | L'OREAL S.A. (FR) | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060088493-A1 | Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers | KRT18, CUTA, MARK1 | ALDH1A1 3552/4885MAPT 366/4885KDM4E 421/4885 |
| US-20060083762-A1 | Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles | KRT18, PRKDC, ACP1 | ALDH1A1 828/4885MAPT 355/4885KDM4E 3279/4885 |
| US-20060115445-A1 | Compositions for treating keratin materials comprising electrophilic monomers and liquid crystal agents | KRT18, PRKDC, CUTA | ALDH1A1 1395/4885MAPT 133/4885KDM4E 2386/4885 |
| US-20100172858-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER | KRT18, DSG1, DSC1 | ALDH1A1 320/4885MAPT 721/4885KDM4E 1488/4885 |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | KRT18, GPX4, NOX4 | ALDH1A1 303/4885MAPT 2098/4885KDM4E 1870/4885 |
| US-20060233731-A1 | Use, for the cosmetic treatment of keratin materials, of a film-forming composition comprising an electrophilic monomer and a non-silicone polymer, conferring a soft coating | KRT18, CUTA, VIM | ALDH1A1 3279/4885MAPT 360/4885KDM4E 564/4885 |
| US-20060083706-A1 | Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant | MITF, CUTA, NACA | ALDH1A1 43/4885MAPT 865/4885KDM4E 4498/4885 |
| US-20060276515-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | EPHX1, EPHX2, NCEH1 | ALDH1A1 385/4885MAPT 4778/4885KDM4E 2114/4885 |
| US-20060088488-A1 | Dyeing composition comprising a mixture of at least one pigment and at least one electrophilic monomer | KRT18, IK, DDR1 | ALDH1A1 155/4885MAPT 248/4885KDM4E 4287/4885 |
| US-20060078522-A1 | Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt | KRT18, DSG1, DSC1 | ALDH1A1 1453/4885MAPT 215/4885KDM4E 2607/4885 |
| US-20120156270-A1 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | EPAS1, PGF, PASK | ALDH1A1 4610/4885MAPT 4165/4885KDM4E 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.