SCHEMBL2993734

SCHEMBL2993734

OB(O)c1cc(F)c(F)c(F)c1F

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA4 P22748 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30502469 1.00 CES2 (0.33) CES2CES1CA1CA2CA4
SCHEMBL29460057 0.80 ALDH1A1 (0.31) CES2CES1
SCHEMBL6483871 0.80 CES2 (0.31) CES2CES1
SCHEMBL5347272 0.80 CA2 (0.32) CES2CES1CA2
SCHEMBL1090760 0.80 HDAC1 (0.33)
SCHEMBL23830110 0.80
SCHEMBL2557587 0.80 ALDH1A1 (0.31) CES2CES1
SCHEMBL29459984 0.80
SCHEMBL20296440 0.78 ALDH1A1 (0.31) CES2CES1
SCHEMBL29517741 0.78 ALDH1A1 (0.31) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025006693-A1 CANNABIDIOL-LIKE COMPOUNDS AND METHODS FOR THE SELECTIVE PREPARATION OF THE SAME UNIVERSITY OF MISSISSIPPI (US) 2025-01-02 WO claimed
US-20100197960-A1 METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL, REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2010-08-05 US claimed
EP-2193134-A1 METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS The Governors Of The University Of Alberta (CA) 2010-06-09 EP claimed
EP-2059227-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY Aeris Therapeutics, Inc. (US) 2009-05-20 EP claimed
WO-2009030022-A1 METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2009-03-12 WO claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed
US-12637438-B2 Protoporphyrinogen oxidase inhibitors ENKO CHEM, INC. (US) 2026-05-26 US disclosed
US-20260068883-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS ENKO CHEM, INC. (US) 2026-03-12 US disclosed
CN-120285294-A Intelligent biological battery for regeneration of diabetic bone defect, and preparation method and application thereof 苏州大学附属第一医院 2025-07-11 CN disclosed
US-12302900-B2 Protoporphyrinogen oxidase inhibitors ENKO CHEM, INC. (US) 2025-05-20 US disclosed
US-20250059185-A1 BICYCLIC HETEROCYCLIC COMPOUNDS USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS HOFFMANN-LA ROCHE INC. (US) 2025-02-20 US disclosed
WO-2025006693-A1 CANNABIDIOL-LIKE COMPOUNDS AND METHODS FOR THE SELECTIVE PREPARATION OF THE SAME UNIVERSITY OF MISSISSIPPI (US) 2025-01-02 WO disclosed
EP-4448522-A1 BICYCLIC HETEROCYCLIC COMPOUNDS USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS F. Hoffmann-La Roche AG (CH) 2024-10-23 EP disclosed
EP-0968158-B1 METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM BASELL POLYOLEFINE GMBH (DE) 2005-08-10 EP disclosed
US-20050033076-A1 Preparation of preparing substituted indanones EQUISTAR CHEMICALS, LP 2005-02-10 US disclosed
WO-2004094481-A2 POLYMERIZATION OF I-BUTENE IN HYDROCARBON MEDIA USING BIS(BORANE)CO-INITIATORS THE UNIVERSITY OF AKRON (US) 2004-11-04 WO disclosed
CN-1474826-A Light emitting device and display ������������ʽ���� 2004-02-11 CN disclosed
EP-1348711-A1 LUMINESCENT ELEMENT AND DISPLAY CANON KABUSHIKI KAISHA (JP) 2003-10-01 EP disclosed
US-20030068526-A1 Such as tetrakis(1-(5-heptyloxyphenyl)isoquinoline-C2,N) (pu-dichloro) iridium (III); for red luminescence; graphic arts CANON KABUSHIKI KAISHA (JP) 2003-04-10 US disclosed
US-20030009046-A1 Preparation of preparing substituted indanones EQUISTAR CHEMICALS, LP 2003-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100197960-A1 METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL, REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS AOC2, AOC3, OXER1 CES2 170/4885CES1 86/4885CA1 403/4885
US-12302900-B2 Protoporphyrinogen oxidase inhibitors PPOX, PNPO, PPIF CES2 1121/4885CES1 683/4885CA1 973/4885
US-20250059185-A1 BICYCLIC HETEROCYCLIC COMPOUNDS USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS MGLL, LIPC, PNLIP CES2 34/4885CES1 36/4885CA1 4405/4885
US-12637438-B2 Protoporphyrinogen oxidase inhibitors PPOX, CYP4X1, CBR3 CES2 717/4885CES1 367/4885CA1 1168/4885
US-20260068883-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS PPOX, CYC1, CBR3 CES2 598/4885CES1 177/4885CA1 875/4885
US-20050033076-A1 Preparation of preparing substituted indanones CYP1A2, CYP2J2, IDH3A CES2 1925/4885CES1 3217/4885CA1 3547/4885
US-20030009046-A1 Preparation of preparing substituted indanones CYP1A2, CYP1B1, CYP1A1 CES2 1961/4885CES1 2736/4885CA1 3105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.