Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945870 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2GPR119DPP4TP53MAPT | |
| SCHEMBL29945924 | 0.78 | TRPV3 (0.44) | SMN1; SMN2DPP4TP53MAPTLMNA | |
| SCHEMBL29945852 | 0.76 | GPR119 (0.53) | SMN1; SMN2GPR119DPP4MAPT | |
| SCHEMBL29945984 | 0.75 | GPR119 (0.41) | GPR119MAPTLMNA | |
| SCHEMBL29945981 | 0.75 | HTR6 (0.41) | HTR2A | |
| SCHEMBL29945994 | 0.74 | GPR119 (0.46) | SMN1; SMN2GPR119TP53LMNA | |
| SCHEMBL29946162 | 0.71 | HTR6 (0.49) | HTR2A | |
| SCHEMBL30568252 | 0.71 | GLP1R (0.51) | — | |
| SCHEMBL7090614 | 0.68 | DRD2 (0.49) | HTR2A | |
| SCHEMBL6491645 | 0.68 | DRD2 (0.49) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |