Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LPL | P06858 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951836 | 0.84 | ENPP2 (0.39) | ENPP2CA2CA1TTRKDM4E | |
| SCHEMBL12759201 | 0.78 | CA2 (0.43) | ENPP2CA2CA1TTRKDM4E | |
| SCHEMBL1083247 | 0.75 | LMNA (0.35) | ENPP2CA2CA1KDM4E | |
| SCHEMBL6988847 | 0.75 | DRD2 (0.44) | CA2 | |
| SCHEMBL29956883 | 0.74 | ALDH1A1 (0.45) | ENPP2CA2CA1TTRALDH1A1 | |
| SCHEMBL442154 | 0.74 | ALDH1A1 (0.45) | ENPP2CA2CA1TTRALDH1A1 | |
| SCHEMBL4027923 | 0.74 | ADRA2A (0.42) | ENPP2CA2CA1TTRALDH1A1 | |
| SCHEMBL8895 | 0.72 | PRKCI (0.51) | — | |
| SCHEMBL1895322 | 0.72 | PRKCI (0.40) | ENPP2CA2CA1 | |
| SCHEMBL19835515 | 0.71 | CA1 (0.39) | CA2CA1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |